In the synthesis of phosphorylated DSIP by global phosphorylation, Aloc protection of the Trp indole prevented the formation of oxidative side products.
In plain wordsIn lab synthesis, a protecting group on tryptophan stopped unwanted oxidation by-products when making phosphorylated DSIP.
- Outcome
- Not applicableSynthesis of phosphorylated DSIP with Aloc indole protection of Trp
- Study
n: not reported in source
Solid-phase peptide synthesis- Outcome group
- Receptor activity and mechanism · Pharmacology
Source sentences
The synthesis of phosphorylated delta sleep inducing peptide (P-DSIP) using the global phosphorylation approach provides another example in which Trp indole protection by Aloc prevents the formation of oxidative side products.
1 context sentence(design, population, supporting numbers)
The synthesis and stability of allyloxycarbonyl (Aloc) indole-protected Trp derivatives and their application in solid-phase peptide synthesis are reported.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).