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Study · In vitro (cell-free) · 1996

1 result

Antitumor and chemopreventive effects of a clomiphene analog, MDL 103,323, in mammary carcinoma.

Bitonti AJ, Baumann RJ, Bush TL, Cashman EA, Wright CL, Prakash NJ

Anticancer research1 Sept 1996Cited by 2 (Europe PMC)

PMID8917350 (opens in a new tab)PepBankPUB-08917350
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cell-free)Activity measurement

    In human estrogen receptor binding tests, enclomiphene had lower affinity than MDL 103,323, which had 5-6 fold greater affinity.

    In plain wordsIn lab tests, enclomiphene bound the human estrogen receptor less strongly than MDL 103,323.

    Peptide
    Enclomiphene
    Outcome
    DecreaseEstrogen receptor affinity
    Study

    humann: not reported in source

    human estrogen receptor
    Comparator
    MDL 103,323
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Measurements

    Relative affinity
    5 to 6 fold
    MDL 103,323 versus enclomiphene

    Source sentences

    Summary
    MDL 103,323 had 5-6 fold greater affinity for the human estrogen receptor than did either tamoxifen or enclomiphene.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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