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Study · Animal study (in vivo) · rat · 1996

2 results

Dose-dependent behavioural effects of two protein-free peptide derivatives on the passive avoidance reaction of rats.

Hutter-Paier B, Eggenreich U, Windisch M

Arzneimittel-Forschung1 Mar 1996Cited by 6 (Europe PMC)

PMID8901142 (opens in a new tab)PepBankPUB-08901142
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In young healthy rats, a single Cerebrolysin injection improved passive avoidance reaction compared with saline controls.

    In plain wordsIn rats, a single Cerebrolysin injection improved passive avoidance reaction compared with saline controls.

    Peptide
    Cerebrolysin
    Outcome
    IncreasePassive avoidance reaction
    Study

    ratn: not reported in source

    2-month-old healthy rats in passive avoidance task
    Comparator
    Saline
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    100 mg/kg b.wt. · subcutaneous injection · one single injectionAs given in this study (rat).

    Source sentences

    Summary
    The results of our experiments demonstrate that already a single injection of PD (100 mg/kg b.wt.), but to a higher extent of PD-exp (1 mg/kg b.wt.) induce an improvement on PA reaction of 2-month-old healthy rats.
    2 context sentences
    Summary · context
    In the presented experiments, rats were treated with only one single injection of PD, PD-exp or saline as a control.
    Summary · context
    Passive avoidance procedure started 24 h after the subcutaneous injection with a single PAR-acquisition training.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In young healthy rats, Cerebrolysin improved passive avoidance reaction to a lesser extent than the experimental derivative PD-exp.

    In plain wordsIn rats, Cerebrolysin improved passive avoidance reaction less than the experimental derivative PD-exp.

    Peptide
    Cerebrolysin
    Outcome
    DecreasePassive avoidance improvement versus PD-exp
    Study

    ratn: not reported in source

    2-month-old healthy rats in passive avoidance task
    Comparator
    PD-exp 1 mg/kg b.wt.
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    100 mg/kg b.wt. · subcutaneous injection · one single injectionAs given in this study (rat).

    Source sentences

    Summary
    The results of our experiments demonstrate that already a single injection of PD (100 mg/kg b.wt.), but to a higher extent of PD-exp (1 mg/kg b.wt.) induce an improvement on PA reaction of 2-month-old healthy rats.
    2 context sentences
    Summary · context
    In the presented experiments, rats were treated with only one single injection of PD, PD-exp or saline as a control.
    Summary · context
    Passive avoidance procedure started 24 h after the subcutaneous injection with a single PAR-acquisition training.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

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