In osteoporotic women, lumbar spine BMD changed by 1.99% with salmon calcitonin and calcium versus -2.66% with calcium alone, a significant difference.
In plain wordsIn osteoporotic women, spine bone density increased with salmon calcitonin and calcium versus a decrease with calcium alone.
- Peptide
- Calcitonin-salmon
- Outcome
- IncreaseLumbar spine BMD
- Study
n: not reported in source
- Comparator
- Calcium alone
- Outcome group
- Bone and joint · Musculoskeletal
- Studied dose
- 200 IU/day, 1 month on and 1 month off · intranasal · 2 yearsAs given in this study (human).
Measurements
- BMD change
- 1.99%
- calcitonin and calcium
- BMD change
- −2.66%
- calcium alone
Source sentences
In the calcitonin-treated group at the end of the study period BMD had increased by 1.99%, SOS by 0.20%, BUA by 0.88% and Stiffness by 2.12%.
4 context sentences(design, population, supporting numbers)
By contrast in the calcium-treated group all parameters had decreased (BMD, -2.66%; SOS, -0.55%; BUA, -3.30%; Stiffness, -6.0%) by the end of the study period.
The differences between groups were significant for BMD, SOS and Stiffness.
To compare US with bone mineral density (BMD), we studied 112 osteoporotic women (age range 50-64 years).
Seventy-eight of them were treated with salmon calcitonin nasal spray (CT; 200 IU/day, 1 month on and 1 month off) and calcium (500 mg/day); 34 patients were given only calcium.