In patients with nasal polyps, immunohistological expression of VIP did not differ from normal nasal mucosa.
In plain wordsIn people with nasal polyps, the body's own VIP was found in the same places and amounts as in normal nasal lining.
- Outcome
- No significant changeVIP expression in nasal polyps versus normal nasal mucosa
- Study
n = 30
- Comparator
- Normal nasal mucosa
- Outcome group
- Endogenous peptide levels · Respiratory
Source sentences
Comparing localization and intensity of the immunohistological reaction in nasal mucosa and nasal polyp tissue, there was no difference in the expression of the three neuroendocrine substances.
3 context sentences(design, population, supporting numbers)
The results indicate that VIP, SP and BFP have an equal distribution in nasal polyps and normal nasal mucosa.
The aim of this study was to compare immunohistologically the presence and distribution of substance P (SP), vasoactive intestinal peptide (VIP) and bombesin-flanking peptide (BFP) in normal nasal mucosa and nasal polyps.
The expression was studied using Formalin-fixed and paraffin-embedded biopsy sections from 20 patients with nasal polyps and 10 controls with normal nasal mucosa from the anterior part of the inferior turbinate.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.