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Study · Not a test of the peptide alone · 1996

2 results

Syntheses and biological activities of parallel and antiparallel homo and hetero bis-cystine dimers of oxytocin and deamino-oxytocin.

Chen L, Bauerová H, Slaninová J, Barany G

Peptide research1 May 1996Cited by 5 (Europe PMC)

PMID8875590 (opens in a new tab)PepBankPUB-08875590

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01LabNot a test of Oxytocin aloneIn vitro (cell-free)Other

    Synthesised disulfide-bridged oxytocin and deamino-oxytocin dimers were isolated in 20% to 40% yield.

    In plain wordsIn lab synthesis, oxytocin dimers were obtained in 20% to 40% yield.

    Peptide
    Oxytocin
    Outcome
    Not applicableIsolated yield of oxytocin and deamino-oxytocin dimers
    Study

    n: not reported in source

    Outcome group
    Synthesis and manufacturing · Pharmacology

    Measurements

    Final isolated yield
    20 to 40%
    dimers

    Source sentences

    Summary
    Final isolated yields of the desired pure dimers were in the 20% to 40% range.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02LabNot a test of Oxytocin aloneOther designActivity measurement

    The oxytocin and deamino-oxytocin dimers had biological activities of 0.2% to 6% of oxytocin, depending on the assay, and some were protracted.

    In plain wordsIn lab tests, the oxytocin dimers were much less active than oxytocin, and some acted for longer.

    Peptide
    Oxytocin
    Outcome
    Not applicableBiological activity of dimers relative to oxytocin
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology

    Measurements

    Biological activity relative to oxytocin
    0.2 to 6%
    dimers, depending on assay

    Source sentences

    Summary
    Biological activities ranged from 0.2% to 6% that of oxytocin, depending on the assay, and were in some cases considerably protracted.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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