In prepubertal male rats, nitric oxide deprivation attenuated GHRP‑6-induced GH secretion.
In plain wordsIn rats, nitric oxide deprivation reduced growth hormone release triggered by GHRP‑6.
- Peptide
- GHRP-6
- Outcome
- DecreaseGH response under NO deprivation
- Study
ratn: not reported in source
prepubertal male rats- Outcome group
- Growth hormone and IGF-1 · Endocrine and hormones
Source sentences
Our results showed that endogenous NO deprivation significantly attenuated in vivo GHRH-, GHRP-6- and NMDA-induced GH secretion in prepubertal male rats.
1 context sentence(design, population, supporting numbers)
was tested in prepubertal male rats after blockade of endogenous NO by pretreatment (45 min before the tests) with the competitive NO synthase (NOS) inhibitors NW-nitro-L-arginine methyl ester (NAME) and NW-nitro-L-arginine (NA).
In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.