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Study · Animal study (in vivo) · rat · 1996

5 results

[The mechanism of the anticonvulsive effect of the delta sleep-inducing peptide under conditions of elevated oxygen pressure].

Mendzheritskiĭ AM, Lysenko AV, Uskova NI, Sametskiĭ EA

Fiziologicheskii zhurnal imeni I.M. Sechenova1 Jan 1996Cited by 1 (Europe PMC)

PMID8829679 (opens in a new tab)PepBankPUB-08829679
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats under elevated oxygen pressure, delta-sleep-inducing peptide protected against seizures.

    In plain wordsIn rats under high oxygen pressure, delta sleep-inducing peptide protected against seizures.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseSeizure protection under elevated oxygen pressure
    Study

    ratn: not reported in source

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Delta-sleep-inducing peptide (DSIP) exerted a protective effect against seizures, the effect depending on the DSIP ability to create an optimal ratio between inhibitory and excitatory amino acid neurotransmitters.
    1 context sentence
    Title · context
    [The mechanism of the anticonvulsive effect of the delta sleep-inducing peptide under conditions of elevated oxygen pressure].
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats, delta-sleep-inducing peptide increased gamma-aminobutyric acid content in the brain cortex.

    In plain wordsIn rats, delta sleep-inducing peptide raised GABA content in the brain cortex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseGamma-aminobutyric acid in rat brain cortex
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of the DSIP dramatically increased the contents of gamma-aminobutyric acid and homocarnosine while decreasing the glutamate and aspartate contents in the rat brain cortex.
    1 context sentence
    Title · context
    [The mechanism of the anticonvulsive effect of the delta sleep-inducing peptide under conditions of elevated oxygen pressure].
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rats, delta-sleep-inducing peptide increased homocarnosine content in the brain cortex.

    In plain wordsIn rats, delta sleep-inducing peptide raised homocarnosine content in the brain cortex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseHomocarnosine in rat brain cortex
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of the DSIP dramatically increased the contents of gamma-aminobutyric acid and homocarnosine while decreasing the glutamate and aspartate contents in the rat brain cortex.
    1 context sentence
    Title · context
    [The mechanism of the anticonvulsive effect of the delta sleep-inducing peptide under conditions of elevated oxygen pressure].
  4. 04AnimalAnimal study (in vivo)Mechanism

    In rats, delta-sleep-inducing peptide decreased glutamate content in the brain cortex.

    In plain wordsIn rats, delta sleep-inducing peptide lowered glutamate content in the brain cortex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseGlutamate in rat brain cortex
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of the DSIP dramatically increased the contents of gamma-aminobutyric acid and homocarnosine while decreasing the glutamate and aspartate contents in the rat brain cortex.
    1 context sentence
    Title · context
    [The mechanism of the anticonvulsive effect of the delta sleep-inducing peptide under conditions of elevated oxygen pressure].
  5. 05AnimalAnimal study (in vivo)Mechanism

    In rats, delta-sleep-inducing peptide decreased aspartate content in the brain cortex.

    In plain wordsIn rats, delta sleep-inducing peptide lowered aspartate content in the brain cortex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseAspartate in rat brain cortex
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of the DSIP dramatically increased the contents of gamma-aminobutyric acid and homocarnosine while decreasing the glutamate and aspartate contents in the rat brain cortex.
    1 context sentence
    Title · context
    [The mechanism of the anticonvulsive effect of the delta sleep-inducing peptide under conditions of elevated oxygen pressure].

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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