In Cos-7 cells expressing the sheep endometrial OTR cDNA, oxytocin induced phosphoinositide turnover, so the receptor was functional.
In plain wordsIn cells carrying the sheep oxytocin receptor gene, oxytocin triggered a cell signal, showing the receptor worked.
- Peptide
- Oxytocin
- Outcome
- IncreaseOxytocin-induced phosphoinositide turnover
- Study
n: not reported in source
Cos-7 cells expressing sheep endometrial OTR cDNA- Outcome group
- Receptor activity and mechanism · Pharmacology
- Studied dose
- Dose not stated
Source sentences
Expression of the cDNA in Cos-7 cells and measurement of oxytocin-induced phosphoinositide turnover confirmed that it coded for a functional product.