In rats given hypertonic saline, a higher percentage of supraoptic oxytocin neurons showed Fos-ir without anesthesia (68%) than with anesthesia (53%).
In plain wordsIn rats given salt injections, more of the body's own oxytocin-containing brain cells were activated without anesthesia than with anesthesia.
- Peptide
- Oxytocin
- Outcome
- IncreaseFos-ir in supraoptic oxytocin neurons after hypertonic saline, without versus with anesthesia
- Study
ratn: not reported in source
supraoptic nucleus oxytocin neurons, Fos immunohistochemistry- Comparator
- Hypertonic saline with prior anesthesia
- Outcome group
- Brain and neuronal activity · Nervous system and cognition
Measurements
- Fos-ir oxytocin neurons
- 68%
- without anesthesia
- Fos-ir oxytocin neurons
- 53%
- with anesthesia
Source sentences
By contrast, a higher percentage of OX-ir neurons was found to exhibit Fos-ir without (68%) than with (53%) anesthesia.
2 context sentences(design, population, supporting numbers)
Expression of Fos protein, detected immunocytochemically, was used to assess the relative responses of supraoptic nucleus (SON) oxytocin- (OX) and vasopressin- (VP) containing neurons to the osmotic vs. the osmotic plus stressful components of intraperitoneal hypertonic saline injections.
The percentage of SON neurons showing Fos-like immunoreactivity (Fos-ir) was quantified for rats receiving general anesthesia only, anesthesia 1 h prior to either isotonic or hypertonic saline injection or no anesthesia prior to hypertonic injection.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.