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Study · Animal study (in vivo) · cat · 1995

2 results

Regulatory peptides as modulators of vagal influence on cardiac rhythm.

Pokrovsky VM, Osadchiy OE

Canadian journal of physiology and pharmacology1 Sept 1995Cited by 13 (Europe PMC)

PMID8748972 (opens in a new tab)DOI10.1139/y95-175 (opens in a new tab)PepBankPUB-08748972
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In anesthetized cats, intravenous delta sleep-inducing peptide potentiated the inhibitory tonic vagal influence on heart rate.

    In plain wordsIn anesthetized cats, delta sleep-inducing peptide strengthened the slowing effect of the vagus nerve on heart rate.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseInhibitory tonic vagal influence on heart rate
    Study

    catn: not reported in source

    Anesthetized cats with right vagus nerve stimulation
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated · intravenousAs given in this study (cat).

    Source sentences

    Summary
    For instance, dalargin (D-Ala2-Leu5-Arg6-enkephalin) and neokyotorphin selectively diminished the inhibitory tonic vagal influence, whereas delta sleep inducing peptide and neurotensin potentiated it.
    1 context sentence
    Summary · context
    When the right vagus nerve of anesthetized cats was stimulated with repetitive bursts of pulses, decelerated heart rate became synchronized to the rhythm of the vagal bursts.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In anesthetized cats, delta sleep-inducing peptide did not change the magnitude of the synchronizing vagal influence on heart rate.

    In plain wordsIn anesthetized cats, delta sleep-inducing peptide did not change how closely heart rate followed vagus nerve bursts.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeSynchronizing vagal influence on heart rate
    Study

    catn: not reported in source

    Anesthetized cats with right vagus nerve stimulation
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated · intravenousAs given in this study (cat).

    Source sentences

    Summary
    For instance, dalargin (D-Ala2-Leu5-Arg6-enkephalin) and neokyotorphin selectively diminished the inhibitory tonic vagal influence, whereas delta sleep inducing peptide and neurotensin potentiated it. The magnitude of synchronizing vagal influence was not modified by these peptides.
    1 context sentence
    Summary · context
    When the right vagus nerve of anesthetized cats was stimulated with repetitive bursts of pulses, decelerated heart rate became synchronized to the rhythm of the vagal bursts.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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