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Study · Measured the body's own peptide · 1996

1 result

Systemic nitroglycerin activates peptidergic and catecholaminergic pathways in rat brain.

Tassorelli C, Joseph SA

Peptides1 Jan 1996Cited by 12 (Europe PMC)

PMID8735971 (opens in a new tab)DOI10.1016/0196-9781(96)00005-8 (opens in a new tab)PepBankPUB-08735971
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats given systemic nitroglycerin, numerous Fos-immunoreactive neurons in the paraventricular and supraoptic nuclei were positive for oxytocin.

    In plain wordsIn rats given nitroglycerin, many activated brain cells in two hypothalamic areas contained the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    IncreaseFos activation in oxytocin-positive hypothalamic neurons after nitroglycerin
    Study

    ratn: not reported in source

    rat brain, immunohistochemistry
    Outcome group
    Brain and neuronal activity · Nervous system and cognition

    Source sentences

    Summary
    In the paraventricular and supraoptic nuclei of the hypothalamus, numerous Fos-immunoreactive neurons were also positive for vasopressin, oxytocin, and corticotropin-releasing factor.
    1 context sentence
    Summary · context
    In this study, we carried out an immunohistochemical evaluation of the neurochemical characteristics of neurons that are activated (i.e., express Fos protein) in response to systemic administration of nitroglycerin.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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