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Study · Animal study (in vivo) · rat · 1994

2 results

[The delta sleep-inducing peptide as a modulator of synaptic ultrastructure].

Mendzheritskiĭ AM, Mikhaleva II, Matsionis AE, Pavilaĭtite PE

Morfologiia (Saint Petersburg, Russia)1 Apr 1994

PMID8718636 (opens in a new tab)PepBankPUB-08718636
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats, DSIP administration caused multidirectional changes in axosomatic and axospinous synapses of the sensorimotor neocortex.

    In plain wordsIn rats, DSIP changed the fine structure of brain synapses in different directions.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    MixedSynaptic ultrastructure in intact animals
    Study

    ratn: not reported in source

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Results of morphometric study of ultrastructure of axosomatic and axospinous synapses of rat sensomotor neocortex after DSIP administration and in hypoxia showed that the peptide administration resulted in multidirectional changes in these type contacts in intact animals.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats, preliminary DSIP administration prevented most of the hypoxia-induced changes in axosomatic and axospinous synapse parameters.

    In plain wordsIn rats, DSIP given beforehand prevented most of the changes in brain synapse structure caused by low oxygen.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseHypoxia-induced synaptic ultrastructure changes
    Study

    ratn: not reported in source

    hypoxia
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Preliminary DSIP administration prevented changes, appearing in hypoxia in most of the parameters studied both in axosomatic and axospinous synapses.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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