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Study · In vitro (cells) · 1995

3 results

The sheep endometrial oxytocin receptor.

Flint AP, Riley PR, Kaluz S, Stewart HJ, Abayasekara DR

Advances in experimental medicine and biology1 Jan 1995Cited by 5 (Europe PMC)

PMID8713978 (opens in a new tab)PepBankPUB-08713978
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In Cos-7 cells, expression of the sheep uterine oxytocin receptor induced oxytocin responsiveness in terms of phosphoinositide turnover.

    In plain wordsIn cells, adding the sheep oxytocin receptor made the cells respond to oxytocin by increasing phosphoinositide turnover.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin responsiveness in Cos-7 cells (phosphoinositide turnover)
    Study

    n: not reported in source

    Cos-7 cells expressing the sheep oxytocin receptor
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    expression of the receptor in Cos-7 cells induces oxytocin responsiveness in terms of phosphoinositide turnover.
    1 context sentence
    Summary · context
    We report here studies on the second messengers involved in the effect of IFN-tau, and on the structure and expression of the oxytocin receptor.

Studies that did not test the peptide alone2

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 02LabNot a test of Oxytocin aloneEx vivo tissueMechanism

    In sheep endometrial explants, expression of the oxytocin receptor was partially blocked by inhibitors or down-regulation of protein kinase C.

    In plain wordsIn lab tests on sheep uterine tissue, blocking protein kinase C partly reduced the making of oxytocin receptors.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin receptor expression in endometrial explants and protein kinase C
    Study

    sheepn: not reported in source

    Ovine endometrial explants
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    The receptor is expressed in ovine endometrial explants during culture, when the explants are taken during the luteal phase of the cycle; this process is partially blocked by inhibitors of protein kinase C
    1 context sentence
    Summary · context
    We report here studies on the second messengers involved in the effect of IFN-tau, and on the structure and expression of the oxytocin receptor.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 03LabNot a test of Oxytocin aloneOther designMechanism

    cDNA sequencing indicated the sheep uterine oxytocin receptor is at least 2 amino acids longer than the receptors of other species.

    In plain wordsIn lab tests, the sheep oxytocin receptor was at least 2 amino acids longer than the receptors of other species.

    Peptide
    Oxytocin
    Outcome
    Not applicableLength of the sheep uterine oxytocin receptor from cDNA sequencing
    Study

    sheepn: not reported in source

    Ovine endometrial explants
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    cDNA sequencing indicates the sheep uterine oxytocin receptor is at least 2 amino acids longer than those of other species
    1 context sentence
    Summary · context
    We report here studies on the second messengers involved in the effect of IFN-tau, and on the structure and expression of the oxytocin receptor.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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