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Study · Measured the body's own peptide · 1996

2 results

The effect of oophorectomy and hormone replacement on neurohypophyseal hormone secretion in women.

Forsling ML, Anderson CH, Wheeler MJ, Raju KS

Clinical endocrinology1 Jan 1996Cited by 6 (Europe PMC)

PMID8706291 (opens in a new tab)DOI10.1046/j.1365-2265.1996.633455.x (opens in a new tab)PepBankPUB-08706291
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In women given oestradiol implants after hysterectomy, plasma oxytocin concentrations fell significantly at 8 and 12 months compared with the value at 6 days.

    In plain wordsIn women with oestradiol implants, the body's own oxytocin levels in blood fell at 8 and 12 months compared with 6 days after surgery.

    Peptide
    Oxytocin
    Outcome
    DecreasePlasma oxytocin with oestradiol implants
    Study

    n: not reported in source

    Comparator
    Value at 6 days
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    but in the groups receiving oestradiol implants concentrations fell significantly at 8 and 12 months compared with the value at 6 days.
    1 context sentence
    Summary · context
    Patients were randomly allocated to receive either transdermal oestradiol patches, 0.05 mg/day, or subdermal implants containing either 50 mg oestradiol or 50 mg oestradiol with 100 mg testosterone.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In women having hysterectomy, oophorectomy had no significant effect on plasma oxytocin concentrations.

    In plain wordsIn women after hysterectomy, removing the ovaries did not change the body's own oxytocin levels in blood.

    Peptide
    Oxytocin
    Outcome
    No significant changePlasma oxytocin after oophorectomy
    Study

    n: not reported in source

    Comparator
    Women with ovaries conserved
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Oophorectomy had no significant effect on plasma oxytocin concentrations
    1 context sentence
    Summary · context
    Patients were randomly allocated to receive either transdermal oestradiol patches, 0.05 mg/day, or subdermal implants containing either 50 mg oestradiol or 50 mg oestradiol with 100 mg testosterone.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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