In rat hypothalamic slices, ANP and BNP inhibited putative vasopressin neurons in the supraoptic nucleus but not putative oxytocin neurons.
In plain wordsIn rat brain slices, the peptides ANP and BNP did not switch off oxytocin-type nerve cells, but did switch off vasopressin-type cells.
- Peptide
- Oxytocin
- Outcome
- Not applicableEffect of ANP and BNP on putative oxytocin neurons in the SON
- Study
ratn: not reported in source
Hypothalamic slice preparations- Outcome group
- Receptor activity and mechanism · Nervous system and cognition
Source sentences
In the SON, these peptides inhibited selectively putative vasopressin neurons but not putative oxytocin neurons, suggesting direct actions of the peptides on vasopressin secretion.
1 context sentence(design, population, supporting numbers)
To clarify direct effects of these peptides on neurons in the regions involved in body water homeostasis, extracellular recordings were made from neurons in the supraoptic nucleus (SON) and regions of anteroventral third ventricle (AV3V) of rat hypothalamic slice preparations.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.