In COSM6 cells expressing the toad mesotocin receptor, oxytocin bound with affinity equal to vasotocin, lower than mesotocin and higher than vasopressin.
In plain wordsIn cells, the toad mesotocin receptor bound oxytocin as well as vasotocin, less well than mesotocin and better than vasopressin.
- Peptide
- Oxytocin
- Outcome
- Not applicableLigand affinity of the toad mesotocin receptor for oxytocin
- Study
toad (Bufo marinus) receptorn: not reported in source
COSM6 cells expressing the toad mesotocin receptor- Outcome group
- Receptor activity and mechanism · Pharmacology
- Studied dose
- Dose not stated
Source sentences
MTR exhibits the following relative order of ligand affinity: mesotocin > vasotocin = oxytocin > vasopressin > hydrin 1, isotocin, hydrin 2.
1 context sentence(design, population, supporting numbers)
In this study, we report the cloning and functional characterization of the cDNA for the mesotocin receptor (MTR) from the urinary bladder of the toad Bufo marinus.