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Study · Animal study (in vivo) · rat · 1995

4 results

Delta-sleep-inducing peptide sequels in the mechanisms of resistance to emotional stress.

Sudakov KV, Coghlan JP, Kotov AV, Salieva RM, Polyntsev YuV, Koplik EV

Annals of the New York Academy of Sciences1 Dec 1995Cited by 10 (Europe PMC)

PMID8597403 (opens in a new tab)DOI10.1111/j.1749-6632.1995.tb44685.x (opens in a new tab)PepBankPUB-08597403
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In control and stressed rats, DSIP administration induced marked changes in substance P levels in hypothalamus and blood plasma.

    In plain wordsIn rats, DSIP caused marked changes in substance P levels in the hypothalamus and blood.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Direction not reportedSubstance P levels in hypothalamus and plasma
    Study

    ratn: not reported in source

    Outcome group
    Anxiety and mood · Endocrine and hormones
    Studied dose
    60 nmol/kgAs given in this study (rat).

    Source sentences

    Summary
    Our experiments showed that DSIP administration induced marked changes in SP, BE, and CORT levels in hypothalamus and blood plasma
    1 context sentence
    Summary · context
    There were 6 groups: 1. control animals, 2. stress animals, 3. rats that received DSIP in a dose of 60 nmol/kg one hour before decapitation, 4. rats in which DSIP was injected 24 hour before decapitation, 5. stressed rats in which DSIP was injected one hour before decapitation during the 5th exposur…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In control and stressed rats, DSIP administration induced marked changes in beta-endorphin levels in hypothalamus and blood plasma.

    In plain wordsIn rats, DSIP caused marked changes in beta-endorphin levels in the hypothalamus and blood.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Direction not reportedBeta-endorphin levels in hypothalamus and plasma
    Study

    ratn: not reported in source

    Outcome group
    Anxiety and mood · Endocrine and hormones
    Studied dose
    60 nmol/kgAs given in this study (rat).

    Source sentences

    Summary
    Our experiments showed that DSIP administration induced marked changes in SP, BE, and CORT levels in hypothalamus and blood plasma.
    1 context sentence
    Summary · context
    There were 6 groups: 1. control animals, 2. stress animals, 3. rats that received DSIP in a dose of 60 nmol/kg one hour before decapitation, 4. rats in which DSIP was injected 24 hour before decapitation, 5. stressed rats in which DSIP was injected one hour before decapitation during the 5th exposur…
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In control and stressed rats, DSIP administration induced marked changes in corticosterone levels in hypothalamus and blood plasma.

    In plain wordsIn rats, DSIP caused marked changes in corticosterone levels in the hypothalamus and blood.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Direction not reportedCorticosterone levels in hypothalamus and plasma
    Study

    ratn: not reported in source

    Outcome group
    Anxiety and mood · Endocrine and hormones
    Studied dose
    60 nmol/kgAs given in this study (rat).

    Source sentences

    Summary
    Our experiments showed that DSIP administration induced marked changes in SP, BE, and CORT levels in hypothalamus and blood plasma.
    1 context sentence
    Summary · context
    There were 6 groups: 1. control animals, 2. stress animals, 3. rats that received DSIP in a dose of 60 nmol/kg one hour before decapitation, 4. rats in which DSIP was injected 24 hour before decapitation, 5. stressed rats in which DSIP was injected one hour before decapitation during the 5th exposur…
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    DSIP stimulated the mechanism of resistance to emotional stress in August rats to a lesser extent than in Wistar rats.

    In plain wordsIn rats, DSIP boosted resistance to emotional stress less in August rats than in Wistar rats.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    MixedStress-resistance mechanism in August rats versus Wistar rats
    Study

    ratn: not reported in source

    Comparator
    Wistar rats
    Outcome group
    Anxiety and mood · Endocrine and hormones
    Studied dose
    60 nmol/kgAs given in this study (rat).

    Source sentences

    Summary
    DSIP administration stimulates the mechanism of resistance in August rats to a lesser extent than in Wistar animals.
    1 context sentence
    Summary · context
    There were 6 groups: 1. control animals, 2. stress animals, 3. rats that received DSIP in a dose of 60 nmol/kg one hour before decapitation, 4. rats in which DSIP was injected 24 hour before decapitation, 5. stressed rats in which DSIP was injected one hour before decapitation during the 5th exposur…

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

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