Skip to content

Study · Animal study (in vivo) · rat · 1994

3 results

Sex difference in sensitivity to exogenous oxytocin in different models of sodium appetite in the rat.

Polidori C, Venturi F, De Caro G

Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma1 Jan 1994Cited by 2 (Europe PMC)

PMID8592919 (opens in a new tab)PepBankPUB-08592919
Publisher pageAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In sodium-depleted male rats, intracerebroventricular oxytocin did not decrease sodium intake.

    In plain wordsIn male rats short of sodium, oxytocin injected into the brain did not lower sodium intake.

    Peptide
    Oxytocin
    Outcome
    No significant changeSodium intake in sodium-depleted male rats
    Study

    ratn: not reported in source

    sodium depletion model of sodium appetite
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    1 microgram/microliter · intracerebroventricular (pulse)As given in this study (rat).

    Source sentences

    Summary
    Sodium depleted male rats showed no decrease in sodium intake after they were given a pulse intracerebroventricular (pICV) injection of either OT (1 microgram/microliter) or the selective OT agonist Tyr4-Gly7OT (1 microgram/microliter).
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In sodium-depleted female rats, intracerebroventricular oxytocin inhibited sodium appetite.

    In plain wordsIn female rats short of sodium, oxytocin injected into the brain lowered sodium appetite.

    Peptide
    Oxytocin
    Outcome
    DecreaseSodium appetite in sodium-depleted female rats
    Study

    ratn: not reported in source

    sodium depletion model of sodium appetite
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    1 microgram/microliter · intracerebroventricular (pulse)As given in this study (rat).

    Source sentences

    Summary
    On the other hand, sodium appetite of sodium depleted female rats were inhibited by the same dose of pICV OT but not by the selective agonist Tyr4-Gly7 OT (1 microgram/microliter).
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In female rats, oxytocin inhibited need-free sodium intake and the sodium appetite that follows furosemide.

    In plain wordsIn female rats, oxytocin lowered sodium intake without need and after furosemide.

    Peptide
    Oxytocin
    Outcome
    DecreaseNeed-free and furosemide-induced sodium intake in female rats
    Study

    ratn: not reported in source

    sodium depletion model of sodium appetite
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    the OT inhibition in females of the need-free sodium intake and of the sodium appetite that occurs after furosemide but not in adrenalectomized or DOCA treated rats

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.