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Study · In vitro (cells) · chick · 1995

5 results

Effect of the tripeptide glycyl-L-histidyl-L-lysine on the proliferation and synthetic activity of chick embryo chondrocytes.

Pesáková V, Novotná J, Adam M

Biomaterials1 Aug 1995Cited by 8 (Europe PMC)

PMID8562779 (opens in a new tab)DOI10.1016/0142-9612(95)93115-t (opens in a new tab)PepBankPUB-08562779
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In chick embryo chondrocytes, GHK stimulated primary culture proliferation mostly on ISC-40 support.

    In plain wordsIn cells from chick embryos, GHK increased growth mostly on ISC-40 support.

    Peptide
    GHK (glycyl-L-histidyl-L-lysine)
    Outcome
    IncreasePrimary culture proliferation on ISC-40
    Study

    chickn: not reported in source

    chick embryo chondrocytes
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Supplementation of culture medium with GHK stimulated chondrocyte proliferation in the primary structure mostly on the ISC-40 support.
    1 context sentence
    Summary · context
    Three different supports are compared: (a) plastic; (b) cartilage collagens; and (c) insoluble skin collagen solubilized under denaturing conditions (ISC-40).
  2. 02LabIn vitro (cells)Efficacy outcome

    In chick embryo chondrocytes, GHK stimulated proliferation on plastic and cartilage collagen mostly in first passages.

    In plain wordsIn cells from chick embryos, GHK increased growth on plastic and cartilage collagen mostly in first passages.

    Peptide
    GHK (glycyl-L-histidyl-L-lysine)
    Outcome
    IncreaseProliferation on plastic and cartilage collagen
    Study

    chickn: not reported in source

    chick embryo chondrocytes
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    On the other two types of supports the stimulatory effect of GHK was expressed mostly in the first passages.
    1 context sentence
    Summary · context
    Three different supports are compared: (a) plastic; (b) cartilage collagens; and (c) insoluble skin collagen solubilized under denaturing conditions (ISC-40).
  3. 03LabIn vitro (cells)Efficacy outcome

    In chick embryo chondrocytes, GHK increased collagen synthesis on both collagen supports.

    In plain wordsIn cells from chick embryos, GHK increased collagen production on both collagen supports.

    Peptide
    GHK (glycyl-L-histidyl-L-lysine)
    Outcome
    IncreaseCollagen synthesis rate
    Study

    chickn: not reported in source

    chick embryo chondrocytes
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The collagen synthetic rate was increased by GHK on both of the collagen supports;
    1 context sentence
    Summary · context
    Three different supports are compared: (a) plastic; (b) cartilage collagens; and (c) insoluble skin collagen solubilized under denaturing conditions (ISC-40).
  4. 04LabIn vitro (cells)Efficacy outcome

    In chick embryo chondrocytes treated with GHK, collagen type II predominated on cartilage collagen support.

    In plain wordsIn cells from chick embryos treated with GHK, collagen type II predominated on cartilage collagen support.

    Peptide
    GHK (glycyl-L-histidyl-L-lysine)
    Outcome
    Not applicableCollagen type II predominance
    Study

    chickn: not reported in source

    chick embryo chondrocytes
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The collagen synthetic rate was increased by GHK on both of the collagen supports; on the cartilage collagen support collagen type II was synthesized predominantly and on the ISC-40 support types I and III were mostly formed.
    1 context sentence
    Summary · context
    Three different supports are compared: (a) plastic; (b) cartilage collagens; and (c) insoluble skin collagen solubilized under denaturing conditions (ISC-40).
  5. 05LabIn vitro (cells)Efficacy outcome

    In chick embryo chondrocytes treated with GHK, collagen types I and III predominated on ISC-40 support.

    In plain wordsIn cells from chick embryos treated with GHK, collagen types I and III predominated on ISC-40 support.

    Peptide
    GHK (glycyl-L-histidyl-L-lysine)
    Outcome
    Not applicableCollagen types I and III predominance
    Study

    chickn: not reported in source

    chick embryo chondrocytes
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The collagen synthetic rate was increased by GHK on both of the collagen supports; on the cartilage collagen support collagen type II was synthesized predominantly and on the ISC-40 support types I and III were mostly formed.
    1 context sentence
    Summary · context
    Three different supports are compared: (a) plastic; (b) cartilage collagens; and (c) insoluble skin collagen solubilized under denaturing conditions (ISC-40).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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