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Study · Animal study (in vivo) · 1995

3 results

[Ratio of neuromediator amino acids in a comparative analysis of the stress protective effects of delta-sleep inducing peptide and piracetam].

Mendzheritskiĭ AM, Uskova NI, Lysenko AV, Matsionis AE, Sametskiĭ EA

Voprosy meditsinskoi khimii1 Sept 1995

PMID8553617 (opens in a new tab)PepBankPUB-08553617
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In animals, administration of DSIP caused a slight decrease in the levels of aspartic acid.

    In plain wordsIn animals, DSIP slightly lowered levels of the amino acid aspartic acid. Piracetam raised it strongly.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseAspartic acid level
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of the peptide caused a slight decrease in the levels of aspartic acid, while piracetam contributed to a marked accumulation of the amino acid.

Studies that did not test the peptide alone2

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 02AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Mechanism

    In intact animals, simultaneous use of DSIP and piracetam accumulated gamma-aminobutyric acid by inhibiting brain glutamate decarboxylase activity.

    In plain wordsIn animals, DSIP and piracetam given together raised brain GABA by lowering the activity of one enzyme.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseBrain GABA accumulation and glutamate decarboxylase activity
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    The GABAergic system was adequate altered after simultaneous use of delta-sleeping peptide and piracetam in intact animals: gamma-butyric acid was accumulated unidirectionally by inhibiting brain glutamate decarboxylase activity.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  2. 03AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome

    In animals, the antistressor and adaptive effects of DSIP and piracetam were augmented when the two drugs were given together before acute emotional stress.

    In plain wordsIn animals, DSIP and piracetam given together before stress had stronger stress-protective effects than each drug alone.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseAntistressor and adaptive effects during acute emotional stress and hypokinesia
    Study

    n: not reported in source

    acute emotional stress with one-hour hypokinesia
    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    The antistressor and adaptive effects of each drug were augmented if they were given simultaneously before acute emotional stress developed in the animals during one-hour hypokinesia; these effects were expressed as stabilized balance of inhibitory and excitatory neurotransmitter amino acids.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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