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Study · Measured the body's own peptide · 1995

3 results

Cerebrospinal fluid neuropeptides in Alzheimer's disease and vascular dementia.

Heilig M, Sjögren M, Blennow K, Ekman R, Wallin A

Biological psychiatry1 Aug 1995Cited by 27 (Europe PMC)

PMID8547442 (opens in a new tab)DOI10.1016/0006-3223(94)00239-y (opens in a new tab)PepBankPUB-08547442
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    Cerebrospinal fluid DSIP levels were slightly higher in patients with Alzheimer's disease than in healthy aged controls.

    In plain wordsPatients with Alzheimer's disease had slightly higher levels of the body's own DSIP in spinal fluid than healthy older people.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseCSF DSIP level in Alzheimer's disease
    Study

    n: not reported in source

    Comparator
    Healthy aged controls
    Outcome group
    Aging markers · Nervous system and cognition

    Source sentences

    Summary
    DSIP was slightly increased in AD
    1 context sentence
    Summary · context
    We have examined the levels of corticotropin-releasing hormone (CRH), beta-endorphine (BEND), delta sleep-inducing peptide (DSIP), somatostatin (SRIF), and neuropeptide Y (NPY) in CSF samples obtained under highly standardized conditions from healthy aged controls and from patients suffering from Al…

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    Cerebrospinal fluid DSIP levels were not increased in patients with vascular dementia compared with healthy aged controls.

    In plain wordsPatients with vascular dementia did not have higher levels of the body's own DSIP in spinal fluid than healthy older people.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeCSF DSIP level in vascular dementia
    Study

    n: not reported in source

    Comparator
    Healthy aged controls
    Outcome group
    Aging markers · Nervous system and cognition

    Source sentences

    Summary
    but not in VAD.
    1 context sentence
    Summary · context
    We have examined the levels of corticotropin-releasing hormone (CRH), beta-endorphine (BEND), delta sleep-inducing peptide (DSIP), somatostatin (SRIF), and neuropeptide Y (NPY) in CSF samples obtained under highly standardized conditions from healthy aged controls and from patients suffering from Al…

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In patients with Alzheimer's disease or vascular dementia, cerebrospinal fluid DSIP concentration did not correlate significantly with duration or degree of illness.

    In plain wordsIn dementia patients, the level of the body's own DSIP in spinal fluid was not linked to how long or how severe the illness was.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeCorrelation of CSF DSIP with duration and degree of illness
    Study

    n: not reported in source

    Outcome group
    Aging markers · Nervous system and cognition

    Source sentences

    Summary
    For none of the peptides did CSF concentrations correlate significantly with duration of illness, nor, with the exception of BEND, with its degree.
    1 context sentence
    Summary · context
    We have examined the levels of corticotropin-releasing hormone (CRH), beta-endorphine (BEND), delta sleep-inducing peptide (DSIP), somatostatin (SRIF), and neuropeptide Y (NPY) in CSF samples obtained under highly standardized conditions from healthy aged controls and from patients suffering from Al…

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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