In women with natural ovulatory cycles, a late follicular oxytocin infusion brought the onset of the LH surge earlier than normal saline.
In plain wordsIn women, oxytocin given before ovulation made the luteinizing hormone surge start earlier than saline did.
- Peptide
- Oxytocin
- Outcome
- DecreaseOnset of the LH surge
- Study
n = 16
- Comparator
- Normal saline
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
- Studied dose
- 256 mIU/min · infusion · 2 hAs given in this study (human).
Source sentences
The women who were administered oxytocin at this late follicular stage had an earlier onset of the LH surge than those who had received saline (P < 0.01).
2 context sentences(design, population, supporting numbers)
In this study the effect of a preovulatory infusion of oxytocin on the onset of the LH surge was investigated in women aged 20-35 years who had natural ovulatory menstrual cycles of lengths between 25-35 days.
One group (n = 8) received an oxytocin infusion of 256 mIU/min for 2 h, the other group (n = 8) received normal saline.