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Study · Not a test of the peptide alone · 1993

1 result

Norepinephrine injections in diagonal band of Broca selectively reduced the activity of vasopressin supraoptic neurons in the rat.

Cunningham JT, Nissen R, Renaud LP

Brain research1 Apr 1993Cited by 16 (Europe PMC)

PMID8518923 (opens in a new tab)DOI10.1016/0006-8993(93)91229-l (opens in a new tab)PepBankPUB-08518923
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In anesthetized rats, norepinephrine injected into the diagonal band of Broca arrested the activity of only 1 of 14 oxytocin-secreting supraoptic neurons.

    In plain wordsIn rats, norepinephrine injected into one brain region stopped the activity of only 1 of 14 oxytocin-producing neurons.

    Peptide
    Oxytocin
    Outcome
    Not applicableArrest of oxytocin-secreting neuron activity by norepinephrine
    Study

    ratn = 14

    Outcome group
    Brain and neuronal activity · Nervous system and cognition

    Measurements

    Oxytocin neurons arrested
    7%
    norepinephrine into diagonal band of Broca

    Source sentences

    Summary
    Injections of 200 nl of 10 microM norepinephrine into the diagonal band of Broca region arrested the spontaneous activity of 80% (12/15) of vasopressin-secreting neurons but only 7% (1/14) of oxytocin secreting-neurons demonstrated a comparable decrease in excitability.
    1 context sentence
    Summary · context
    Extracellular recordings were obtained from antidromically identified supraoptic neurons in pentobarbital anesthetized rats using a transpharyngeal approach.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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