Skip to content

Study · Measured the body's own peptide · 1993

3 results

Daily variations in concentration of vasoactive intestinal peptide immunoreactivity in hypothalamic nuclei of rats rendered diurnal by restricted-schedule feeding.

Morin AJ, Denoroy L, Jouvet M

Neuroscience letters1 Apr 1993Cited by 13 (Europe PMC)

PMID8515863 (opens in a new tab)DOI10.1016/0304-3940(93)90498-a (opens in a new tab)PepBankPUB-08515863
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats fed only in diurnal hours, the daily pattern of the body's own VIP-like immunoreactivity in the suprachiasmatic nucleus was perturbed and its minimum advanced by 4 h.

    In plain wordsIn rats fed only by day, the body's own VIP rhythm in a brain clock area was disturbed and its low came 4 hours earlier.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableDaily VIP-like immunoreactivity pattern in suprachiasmatic nucleus
    Study

    ratn: not reported in source

    Rats on restricted-schedule diurnal feeding
    Outcome group
    Circadian rhythm · Nervous system and cognition

    Source sentences

    Summary
    In these conditions which inverse the paradoxical sleep rhythm, the VIP-LI pattern is perturbed and its minimum advanced by 4 h in the SCN.
    1 context sentence
    Summary · context
    In order to determine whether these variations are linked to the light-dark cycle or are a consequence of sleep-wake rhythm expression, we dissociated these two parameters by restricting feeding to diurnal hours.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats fed only in diurnal hours, the daily pattern of the body's own VIP-like immunoreactivity in the periventricular nucleus was maintained but its minimum advanced by 4 h.

    In plain wordsIn rats fed only by day, the body's own VIP rhythm in the periventricular area kept its pattern; its low came 4 hours earlier.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableDaily VIP-like immunoreactivity pattern in periventricular nucleus
    Study

    ratn: not reported in source

    Rats on restricted-schedule diurnal feeding
    Outcome group
    Circadian rhythm · Nervous system and cognition

    Source sentences

    Summary
    In the PeVN, the daily pattern is maintained but the minimum is also advanced by 4 h.
    1 context sentence
    Summary · context
    In order to determine whether these variations are linked to the light-dark cycle or are a consequence of sleep-wake rhythm expression, we dissociated these two parameters by restricting feeding to diurnal hours.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In rats fed only in diurnal hours, the daily rhythm of the body's own VIP-like immunoreactivity in the paraventricular nucleus was abolished.

    In plain wordsIn rats fed only by day, the daily rhythm of the body's own VIP in the paraventricular brain area disappeared.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreaseDaily VIP-like immunoreactivity rhythm in paraventricular nucleus
    Study

    ratn: not reported in source

    Rats on restricted-schedule diurnal feeding
    Outcome group
    Circadian rhythm · Nervous system and cognition

    Source sentences

    Summary
    Finally, the rhythm is abolished in the PaVN.
    1 context sentence
    Summary · context
    In order to determine whether these variations are linked to the light-dark cycle or are a consequence of sleep-wake rhythm expression, we dissociated these two parameters by restricting feeding to diurnal hours.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.