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Study · Randomized controlled trial · 1993

3 results

The luteal phase after ovulation induction with human menopausal gonadotropin and one versus two doses of a gonadotropin-releasing hormone agonist.

Corson SL, Batzer FR, Gocial B, Maislin G

Fertility and sterility1 Jun 1993Cited by 10 (Europe PMC)

PMID8495774 (opens in a new tab)DOI10.1016/s0015-0282(16)55985-8 (opens in a new tab)PepBankPUB-08495774
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In infertile women primed with hMG, two nafarelin doses sustained LH release more effectively than one dose.

    In plain wordsIn infertile women primed with hMG, two nafarelin doses sustained LH release more effectively than one dose.

    Peptide
    Nafarelin
    Outcome
    IncreaseSustained LH release
    Study

    n: not reported in source

    Comparator
    One dose of nafarelin
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Two doses · intranasalAs given in this study (human).

    Source sentences

    Summary
    The two-dose regimen was more effective than one dose for sustained LH release.
    3 context sentences
    Summary · context
    Prospective, randomized double-blind protocol using one or two doses of intranasal nafarelin.
    Summary · context
    PATIENTS, INTERVENTIONS: Infertile women not conceiving after use of clomiphene citrate for at least 6 months who were given hMG and nafarelin.
    Summary · context
    No luteal support was given.
  2. 02HumanNon-randomized trialEfficacy outcome

    In infertile women, luteal progesterone after nafarelin was lower than usually seen with gonadotropin-hCG therapy without luteal support.

    In plain wordsIn infertile women, luteal progesterone after nafarelin was lower than usually seen with gonadotropin-hCG therapy without luteal support.

    Peptide
    Nafarelin
    Outcome
    DecreaseLuteal progesterone
    Study

    n: not reported in source

    Comparator
    Usual gonadotropin-hCG therapy without luteal support
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Luteal phase P values and luteal phase duration were both less than usually seen with gonadotropin hCG therapy in the absence of luteal phase support.
    3 context sentences
    Summary · context
    Prospective, randomized double-blind protocol using one or two doses of intranasal nafarelin.
    Summary · context
    PATIENTS, INTERVENTIONS: Infertile women not conceiving after use of clomiphene citrate for at least 6 months who were given hMG and nafarelin.
    Summary · context
    No luteal support was given.
  3. 03HumanNon-randomized trialEfficacy outcome

    In infertile women, luteal duration after nafarelin was shorter than usually seen with gonadotropin-hCG therapy without luteal support.

    In plain wordsIn infertile women, luteal duration after nafarelin was shorter than usually seen with gonadotropin-hCG therapy without luteal support.

    Peptide
    Nafarelin
    Outcome
    DecreaseLuteal phase duration
    Study

    n: not reported in source

    Comparator
    Usual gonadotropin-hCG therapy without luteal support
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Luteal phase P values and luteal phase duration were both less than usually seen with gonadotropin hCG therapy in the absence of luteal phase support.
    3 context sentences
    Summary · context
    Prospective, randomized double-blind protocol using one or two doses of intranasal nafarelin.
    Summary · context
    PATIENTS, INTERVENTIONS: Infertile women not conceiving after use of clomiphene citrate for at least 6 months who were given hMG and nafarelin.
    Summary · context
    No luteal support was given.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:36 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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