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Study · Animal study (in vivo) · rat · 1993

2 results

[Changes in the intensity of free-radical reactions in the organs of rats under hypokinetic stress and with protection by the delta sleep-inducing peptide and its tyrosine-containing analog].

Rikhireva GT, Makletsova MG, Mendzherkitskiĭ AM, Vartanian LS, Gurevich SM, Lozovskaia EL, Kopylovskiĭ SA, Rylova AV, Prudchenko IA, Mikhaleva II

Izvestiia Akademii nauk. Seriia biologicheskaia1 Mar 1993Cited by 1 (Europe PMC)

PMID8471976 (opens in a new tab)PepBankPUB-08471976
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats under hypokinesia, preliminary injection of DSIP showed an antioxidant effect on stress-induced free-radical changes.

    In plain wordsIn rats under hypokinetic stress, DSIP given before the stress had an antioxidant effect.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseFree-radical reactions during hypokinetic stress (antioxidant effect)
    Study

    ratn: not reported in source

    Outcome group
    Aging markers · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The data point to the antioxidant effect of the administration of the peptides before hypokinesia.
    1 context sentence
    Summary · context
    The effect of the preliminary injection of DSIP and its analogue ID-2 on these dynamics has also been studied.
  2. 02LabIn vitro (cell-free)Mechanism

    In a model system, interaction constants between DSIP and the superoxide radical O2- were determined.

    In plain wordsIn lab tests, the study measured how strongly DSIP reacts with a reactive oxygen molecule.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableInteraction constants between DSIP and superoxide radical
    Study

    n: not reported in source

    Model system
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Using a model system constants of the interaction between DSIP or ID-2 and O2-. have been determined.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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