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Study · Non-randomized trial · n = 37 · 1993

4 results

Influence of sex, age and adrenergic pathways on the growth hormone response to GHRP-6.

Peñalva A, Pombo M, Carballo A, Barreiro J, Casanueva FF, Dieguez C

Clinical endocrinology1 Jan 1993Cited by 41 (Europe PMC)

PMID8435889 (opens in a new tab)DOI10.1111/j.1365-2265.1993.tb00977.x (opens in a new tab)PepBankPUB-08435889
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanNon-randomized trialMechanism

    GH responses to GHRP‑6 did not differ between children and adult men or women at different menstrual stages.

    In plain wordsGrowth hormone responses to GHRP‑6 were similar in children, adult men, and women at different menstrual stages.

    Peptide
    GHRP-6
    Outcome
    No significant changeGH response across age and sex groups
    Study

    n = 37

    Comparator
    Children, adult men, and adult women at different menstrual stages
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    1 microgram/kg · intravenousAs given in this study (human).

    Source sentences

    Summary
    No differences in GH responses to GHRP-6 were found between children and normal adult male or female subjects at different stages of their menstrual cycle.

Studies that did not test the peptide alone3

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 02HumanNot a test of GHRP-6 aloneNon-randomized trialMechanism

    In adult men, propranolol did not modify GH responses to GHRP‑6.

    In plain wordsIn men, propranolol did not change growth hormone responses compared with GHRP‑6 alone.

    Peptide
    GHRP-6
    Outcome
    No significant changePropranolol-modified GH response
    Study

    n = 8

    Comparator
    GHRP-6 alone
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Administration of propranolol and clonidine did not modify the GH responses to GHRP-6 in male adults.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 03HumanNot a test of GHRP-6 aloneNon-randomized trialMechanism

    In adult men, clonidine did not modify GH responses to GHRP‑6.

    In plain wordsIn men, clonidine did not change growth hormone responses compared with GHRP‑6 alone.

    Peptide
    GHRP-6
    Outcome
    No significant changeClonidine-modified GH response
    Study

    n = 8

    Comparator
    GHRP-6 alone
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Administration of propranolol and clonidine did not modify the GH responses to GHRP-6 in male adults.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  3. 04HumanNot a test of GHRP-6 aloneNon-randomized trialMechanism

    In adult men, prazosin increased plasma GH responses compared with GHRP‑6 alone.

    In plain wordsIn men, prazosin increased growth hormone responses compared with GHRP‑6 alone.

    Peptide
    GHRP-6
    Outcome
    IncreasePrazosin-modified GH response
    Study

    n = 8

    Comparator
    GHRP-6 alone
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    In contrast, prazosin administration induced an increase in plasma GH levels that was statistically different from that of GHRP-6 alone (. < 0.05 between area under curve).

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:59 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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