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Study · Animal study (in vivo) · mouse · 1993

2 results

Restorative effect of short term administration of thymulin on thymus-dependent antibody production in restraint-stressed mice.

Okamoto M, Morishita M, Setoguchi C, Nakata K

International journal of immunopharmacology1 Aug 1993Cited by 5 (Europe PMC)

PMID8407057 (opens in a new tab)DOI10.1016/0192-0561(93)90149-s (opens in a new tab)PepBankPUB-08407057
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In restraint-stressed mice, thymulin restored antibody production against SRBC to near normal levels.

    In plain wordsIn stressed mice, thymulin restored antibody production toward normal levels compared with stressed mice without thymulin.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseAntibody production under restraint stress
    Study

    mousen: not reported in source

    Restraint-stressed mice
    Comparator
    Stressed mice without thymulin
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1 ng/kg · 3 daysAs given in this study (mouse).

    Source sentences

    Summary
    A 3-day period of administration of thymulin (1 ng/kg) restored antibody production to close to the normal level
    1 context sentence
    Summary · context
    We investigated the restorative effect of thymulin on the stress-induced reduction in the production of antibodies against SRBC in mice.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In normal mice, thymulin did not affect antibody production.

    In plain wordsIn normal mice, thymulin did not change antibody production.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeAntibody production in normal mice
    Study

    mousen: not reported in source

    Normal mice
    Comparator
    Normal mice without thymulin
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1 ng-1 microgram/kg · 3 daysAs given in this study (mouse).

    Source sentences

    Summary
    whereas thymulin (1 ng-1 microgram/kg) did not affect antibody production in normal mice.
    1 context sentence
    Summary · context
    We investigated the restorative effect of thymulin on the stress-induced reduction in the production of antibodies against SRBC in mice.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 13:55 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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