In uterine explants from ovariectomized ewes, culture with oxytocin for 96 h significantly reduced oxytocin receptor binding activity compared with control medium.
In plain wordsIn ewe uterine tissue grown in the lab, oxytocin lowered oxytocin receptor binding compared with control medium.
- Peptide
- Oxytocin
- Outcome
- DecreaseOxytocin receptor binding activity after 96 h culture with oxytocin
- Study
sheepn: not reported in source
uterine explants from ovariectomized ewes- Comparator
- Control medium
- Outcome group
- Receptor activity and mechanism · Reproductive and sexual health
- Studied dose
- Dose not stated · 96 hAs given in this study (sheep).
Source sentences
Progesterone and oxytocin significantly reduced receptor binding activity in explants cultured for 96 h (P < 0.05).
2 context sentences(design, population, supporting numbers)
The effects of oestradiol, progesterone, oxytocin and combinations of these hormones on oxytocin receptor binding in explants of uteri from ovariectomized ewes were determined.
Receptor binding remained unchanged after 96 h in culture in control medium.