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Study · Non-randomized trial · 1993

6 results

GH releasing peptides--structure and kinetics.

Bowers CY

The Journal of pediatric endocrinology1 Jan 1993Cited by 84 (Europe PMC)

PMID8374685 (opens in a new tab)DOI10.1515/jpem.1993.6.1.21 (opens in a new tab)PepBankPUB-08374685
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In children with various degrees of GH deficiency, oral GHRP‑6 induced GH release.

    In plain wordsIn children with different degrees of growth hormone deficiency, GHRP‑6 taken by mouth released growth hormone.

    Peptide
    GHRP-6
    Outcome
    IncreaseGH release after oral GHRP-6 in children with GH deficiency
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · oralAs given in this study (human).

    Source sentences

    Summary
    Additionally, GH release was induced by oral GHRP-6 in children with various degrees of GH deficiency.
  2. 02HumanOther designEfficacy outcome

    In humans, GHRP‑2 released GH after oral administration.

    In plain wordsIn people, GHRP‑2 taken by mouth released growth hormone.

    Peptide
    GHRP-2
    Outcome
    IncreaseGH release after oral GHRP-2
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · oralAs given in this study (human).

    Source sentences

    Summary
    Particularly note-worthy is that GHRP-6, GHRP-1 AND GHRP-2 all release GH after oral administration.
    1 context sentence
    Summary · context
    In the present studies, the GH responses and serum irGHRP levels after i.v., s.c. and oral administration have been determined in normal younger men and/or women.
  3. 03HumanOther designEfficacy outcome

    In humans, near maximal amounts of GH were released after oral administration of GHRP-1 and GHRP‑2.

    In plain wordsIn people, GHRP‑2 taken by mouth released near maximal amounts of growth hormone.

    Peptide
    GHRP-2
    Outcome
    IncreaseNear maximal GH release after oral GHRP-2
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · oralAs given in this study (human).

    Source sentences

    Summary
    Near maximal amounts of GH can be released after GHRP-1 and GHRP-2 oral administration.
    1 context sentence
    Summary · context
    In the present studies, the GH responses and serum irGHRP levels after i.v., s.c. and oral administration have been determined in normal younger men and/or women.

Studies that did not test the peptide alone3

In this study, the peptide was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking the peptide.

  1. 04HumanNot a test of GHRP-6 aloneNon-randomized trialEfficacy outcome

    In normal younger men and women, GH was very effectively released by each route of GHRP administration.

    In plain wordsIn healthy younger adults, growth hormone-releasing peptide gave strong growth hormone release by every route tested.

    Peptide
    GHRP-6
    Outcome
    IncreaseGH release by an unnamed GHRP after intravenous, subcutaneous and oral dosing
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    By each route of administration GH was very effectively released.
    1 context sentence
    Summary · context
    In the present studies, the GH responses and serum irGHRP levels after i.v., s.c. and oral administration have been determined in normal younger men and/or women.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 05HumanNot a test of GHRP-2 aloneOther designEfficacy outcome

    In humans, GHRP-6, GHRP-1 and GHRP‑2 as a group released GH more efficaciously than GHRH 1-44 NH2.

    In plain wordsIn people, three growth hormone releasing peptides, including GHRP‑2, released more growth hormone than GHRH 1-44 NH2.

    Peptide
    GHRP-2
    Outcome
    IncreaseGH release by the three GHRPs versus GHRH 1-44
    Study

    n: not reported in source

    Comparator
    GHRH 1-44 NH2
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    All 3 GHRPs release GH more efficaciously than GHRH 1-44 NH2 in humans.
    1 context sentence
    Summary · context
    In the present studies, the GH responses and serum irGHRP levels after i.v., s.c. and oral administration have been determined in normal younger men and/or women.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  3. 06HumanNot a test of GHRP-2 aloneOther designEfficacy outcome

    In normal younger men and/or women, GH was very effectively released by GHRPs by each route of administration (i.v., s.c. and oral).

    In plain wordsIn healthy younger people, growth hormone releasing peptides released growth hormone well by injection into a vein, under the skin and by mouth.

    Peptide
    GHRP-2
    Outcome
    IncreaseGH release by GHRPs after i.v., s.c. and oral dosing
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    By each route of administration GH was very effectively released.
    1 context sentence
    Summary · context
    In the present studies, the GH responses and serum irGHRP levels after i.v., s.c. and oral administration have been determined in normal younger men and/or women.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Versions 4 to 18Current

    28 Oct 2026, 02:02 UTC

    The same notice was added 15 times, first on 13 Oct 2026, 21:44 UTC. The status did not change between them.

    Study results updated

  2. Version 3

    13 Oct 2026, 16:31 UTC

    Study data updated · source update from Europe PMC

  3. Version 2

    12 Oct 2026, 12:58 UTC

    Study results updated

  4. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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