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Study · Animal study (in vivo) · rat · 1993

5 results

[A quantitative pharmaco-electroencephalographic analysis of the action of bromantane].

Krapivin SV, Sergeeva SA, Morozov IS

Biulleten' eksperimental'noi biologii i meditsiny1 Nov 1993Cited by 1 (Europe PMC)

PMID8312546 (opens in a new tab)PepBankPUB-08312546
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats, bromantane decreased total EEG spectral power.

    In plain wordsIn rats, bromantane decreased total brain-wave spectral power.

    Peptide
    Bromantane
    Outcome
    DecreaseTotal EEG spectral power
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Bromantane leads to decreases in the total and absolute powers of all frequency bands of EEG spectra, changes structural spectra in the cortex and in hippocamp--decreases the relative power of theta-band and increases the relative power of beta 1, 2-activity.
    1 context sentence
    Summary · context
    The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behavior was investigated.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats, bromantane decreased absolute power across all EEG frequency bands.

    In plain wordsIn rats, bromantane decreased absolute power across all brain-wave frequency bands.

    Peptide
    Bromantane
    Outcome
    DecreaseAbsolute EEG band power
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Bromantane leads to decreases in the total and absolute powers of all frequency bands of EEG spectra, changes structural spectra in the cortex and in hippocamp--decreases the relative power of theta-band and increases the relative power of beta 1, 2-activity.
    1 context sentence
    Summary · context
    The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behavior was investigated.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rats, bromantane decreased relative theta-band power in cortical and hippocampal EEG spectra.

    In plain wordsIn rats, bromantane decreased relative theta brain-wave power in the cortex and hippocampus.

    Peptide
    Bromantane
    Outcome
    DecreaseRelative theta power
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Bromantane leads to decreases in the total and absolute powers of all frequency bands of EEG spectra, changes structural spectra in the cortex and in hippocamp--decreases the relative power of theta-band and increases the relative power of beta 1, 2-activity.
    1 context sentence
    Summary · context
    The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behavior was investigated.
  4. 04AnimalAnimal study (in vivo)Mechanism

    In rats, bromantane increased relative beta activity in cortical and hippocampal EEG spectra.

    In plain wordsIn rats, bromantane increased relative beta brain-wave activity in the cortex and hippocampus.

    Peptide
    Bromantane
    Outcome
    IncreaseRelative beta activity
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Bromantane leads to decreases in the total and absolute powers of all frequency bands of EEG spectra, changes structural spectra in the cortex and in hippocamp--decreases the relative power of theta-band and increases the relative power of beta 1, 2-activity.
    1 context sentence
    Summary · context
    The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behavior was investigated.
  5. 05AnimalAnimal study (in vivo)Mechanism

    In rats, bromantane produced a two-phase EEG effect that persisted throughout recording.

    In plain wordsIn rats, bromantane produced two peaks of brain-wave effects that persisted throughout recording.

    Peptide
    Bromantane
    Outcome
    Not applicableEEG effect time course
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Measurements

    First maximum
    2 to 3 hours
    after administration
    Second maximum
    6 to 7 hours
    after administration
    Recording duration
    8 h
    EEG recording

    Source sentences

    Summary
    The basic feature of bromantane's action is a two-phase effect (its maximum occurs 2-3 and 6-7 hours after administration), which remains up to 8 h of EEG recording.
    1 context sentence
    Summary · context
    The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behavior was investigated.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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