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Study · Animal study (in vivo) · 1993

2 results

[Radioprotective effect of synthetic immunomodulators on hemopoietic CFU-S].

Sëmina OV, Semenets TN, Deĭgin VI, Korotkov AM, Poverennyĭ AM

Radiatsionnaia biologiia, radioecologiia1 Nov 1993Cited by 1 (Europe PMC)

PMID8293106 (opens in a new tab)PepBankPUB-08293106
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In the irradiated CFU-S model, thymogen reduced damage from ionizing radiation by half compared with control.

    In plain wordsIn animals, thymogen reduced radiation damage to blood-forming colony units by half compared with control.

    Peptide
    Thymogen (oglufanide)
    Outcome
    DecreaseRadiation damage to CFU-S
    Study

    n: not reported in source

    irradiated hemopoietic CFU-S
    Comparator
    Control
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Both thymogen and thymohexin were demonstrated to be able to reduce the damaging effect of ionizing radiation (1 Gy) on CFU-S by half.
    1 context sentence
    Summary · context
    The radiotherapeutic effect of thymogen (Glu-Trp) and thymohexin (Arg-Lys-Asp-Val-Tyr-Arg) synthetic peptide immunomodulators was investigated.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In the irradiated CFU-S model, thymogen treatment after irradiation increased CFU-S population restoration compared with control.

    In plain wordsIn animals, thymogen increased recovery of blood-forming colony units after irradiation compared with control.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseCFU-S population restoration
    Study

    n: not reported in source

    irradiated hemopoietic CFU-S
    Comparator
    Control
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The treatment by these preparations after irradiation at dose of 4 Gy leads to more intensive restoration of CFU-S population as compared with control.
    1 context sentence
    Summary · context
    The radiotherapeutic effect of thymogen (Glu-Trp) and thymohexin (Arg-Lys-Asp-Val-Tyr-Arg) synthetic peptide immunomodulators was investigated.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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