In fetal rat testis cultures, thymulin supplementation produced about twice as many germ cells as synthetic medium, corticosterone medium, or thymic co-culture with corticosterone.
In plain wordsIn lab tests, thymulin approximately doubled rat germ cell numbers versus synthetic medium, corticosterone medium, or thymic co-culture with corticosterone.
- Outcome
- IncreaseGerm cell number
- Study
ratn: not reported in source
Fetal testis explants- Comparator
- Synthetic medium, corticosterone-supplemented medium, or thymic co-culture with corticosterone
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
- Studied dose
- Dose not stated · 1 or 2 daysAs given in this study (rat).
Measurements
- Germ cell number
- ≈ 2 fold
- thymulin medium versus other conditions
Source sentences
The numbers of germ cells were about 2-fold greater in testes cultured with fragments of thymus, or in thymulin-supplemented medium than in all the other experimental conditions.
1 context sentence(design, population, supporting numbers)
Testes from 13.5-day-old rat foetuses were cultured in vitro for 1 or 2 days: 1) in synthetic medium; 2) in thymulin- or corticosterone supplemented medium; 3) in co-culture with fragments of foetal thymus; 4) in co-culture with fragments of foetal thymus in corticosterone-supplemented medium.