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Study · Measured the body's own peptide · 1994

1 result

The control of circadian rhythms and the levels of vasoactive intestinal peptide mRNA in the suprachiasmatic nucleus are altered in spontaneously hypertensive rats.

Peters RV, Zoeller RT, Hennessey AC, Stopa EG, Anderson G, Albers HE

Brain research1 Mar 1994Cited by 36 (Europe PMC)

PMID8205475 (opens in a new tab)DOI10.1016/0006-8993(94)91733-7 (opens in a new tab)PepBankPUB-08205475
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In spontaneously hypertensive rats, VIP mRNA in the suprachiasmatic nucleus was significantly higher than in Wistar-Kyoto control rats.

    In plain wordsIn rats, the body's own VIP messenger RNA in a brain clock region was higher in hypertensive rats than in normal-pressure rats.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    IncreaseVIP mRNA level in the suprachiasmatic nucleus
    Study

    ratn: not reported in source

    spontaneously hypertensive rats and Wistar-Kyoto rats
    Comparator
    Wistar-Kyoto rats
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Using in situ hybridization, the SCN levels of mRNA encoding VIP were found to be significantly greater in SHR rats
    1 context sentence
    Summary · context
    Because VIP levels are abnormally high in SHR rats the present study examined whether the mechanisms controlling circadian rhythms are also altered in SHR rats.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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