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Study · Measured the body's own peptide · 1994

3 results

Crosstalk in the magnocellular system during osmotic stimulation of one supraoptic nucleus.

Summy-Long JY, Neumann I, Terrell ML, Koehler E, Gestl S, Landgraf R, Kadekaro M

Brain research bulletin1 Jan 1994Cited by 7 (Europe PMC)

PMID8193918 (opens in a new tab)DOI10.1016/0361-9230(94)90228-3 (opens in a new tab)PepBankPUB-08193918
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In virgin and lactating rats, hypertonic microdialysis of one supraoptic nucleus area increased oxytocin release in the nucleus.

    In plain wordsIn rats, salty fluid placed in one brain area raised the body's own oxytocin release there.

    Peptide
    Oxytocin
    Outcome
    IncreaseIntranuclear oxytocin release in the supraoptic nucleus
    Study

    ratn: not reported in source

    Comparator
    dialysis with CSF
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    In both virgin and lactating rats, microdialysis of HS-CSF unilaterally into the SON area significantly (p < 0.05) increased release of OT in the nucleus and into plasma, which was associated with enhanced (p < 0.05) metabolic activity in the ipsilateral and contralateral SON and the neural lobe but not in either PVN.
    1 context sentence
    Summary · context
    intranuclear release of oxytocin (OT) was stimulated by microdialysis of hypertonic CSF containing 1 M NaCl (HS-CSF) into the right SON area and glucose metabolism of both SONs and PVNs and the neural lobe of virgin and lactating (10-12 day) rats

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In virgin and lactating rats, hypertonic microdialysis into the supraoptic nucleus area increased oxytocin release into plasma.

    In plain wordsIn rats, salty fluid placed in one brain area raised the body's own oxytocin in blood.

    Peptide
    Oxytocin
    Outcome
    IncreasePlasma oxytocin after hypertonic stimulation of supraoptic nucleus
    Study

    ratn: not reported in source

    Comparator
    dialysis with CSF
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    In both virgin and lactating rats, microdialysis of HS-CSF unilaterally into the SON area significantly (p < 0.05) increased release of OT in the nucleus and into plasma, which was associated with enhanced (p < 0.05) metabolic activity in the ipsilateral and contralateral SON and the neural lobe but not in either PVN.
    1 context sentence
    Summary · context
    intranuclear release of oxytocin (OT) was stimulated by microdialysis of hypertonic CSF containing 1 M NaCl (HS-CSF) into the right SON area and glucose metabolism of both SONs and PVNs and the neural lobe of virgin and lactating (10-12 day) rats

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats given hypertonic stimulation, lactating rats had less plasma oxytocin than virgin rats.

    In plain wordsIn rats, lactating females had less of the body's own oxytocin in blood than virgin females during salty-fluid stimulation.

    Peptide
    Oxytocin
    Outcome
    DecreasePlasma oxytocin in lactating versus virgin rats during hypertonic stimulation
    Study

    ratn: not reported in source

    Comparator
    virgin rats
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Compared with virgins, lactating rats were less active, had lower (p < 0.05) glucose utilization in the hypothalamo-neurohypophysial system, and less (p < 0.05) OT in plasma during microdialysis of HS-CSF into the SON area.
    1 context sentence
    Summary · context
    intranuclear release of oxytocin (OT) was stimulated by microdialysis of hypertonic CSF containing 1 M NaCl (HS-CSF) into the right SON area and glucose metabolism of both SONs and PVNs and the neural lobe of virgin and lactating (10-12 day) rats

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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