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Study · Not a test of the peptide alone · 1994

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Synthesis of methylated phenylalanines via hydrogenolysis of corresponding 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids. Synthesis and biological activity of oxytocin analogs with methylated phenylalanines in position 2.

Majer P, Slaninová J, Lebl M

International journal of peptide and protein research1 Jan 1994Cited by 10 (Europe PMC)

PMID8138352 (opens in a new tab)DOI10.1111/j.1399-3011.1994.tb00376.x (opens in a new tab)PepBankPUB-08138352
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01LabNot a test of Oxytocin aloneOther designActivity measurement

    Oxytocin analogs with methylated D-phenylalanines in position 2 were potent uterotonic inhibitors.

    In plain wordsIn lab tests, oxytocin analogs carrying modified D-phenylalanine blocked uterus contraction strongly.

    Peptide
    Oxytocin
    Outcome
    Not applicableUterotonic activity of oxytocin analogs with methylated phenylalanine in position 2
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    Incorporation of the methylated phenylalanines into position 2 of oxytocin led to, in the case of the D-isomers, potent uterotonic inhibitors.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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