Localization of oxytocin binding sites in the thoracic and upper lumbar spinal cord of the adult and postnatal rat: a histoautoradiographic study.

Reiter MK, Kremarik P, Freund-Mercier MJ, Stoeckel ME, Desaulles E, Feltz P

The European journal of neuroscience1 Jan 1994Cited by 66 (Europe PMC)

PMID8130936DOI10.1111/j.1460-9568.1994.tb00251.xPepBankPUB-08130936

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone7

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

01LabNot a test of Oxytocin aloneEx vivo tissueMechanism
In rat spinal cord, oxytocin binding sites were present on all transverse sections in the dorsal horn, scattered over laminae I and II.
In plain wordsIn lab tests on rat spinal cord, oxytocin binding sites were found in the dorsal horn.
Peptide
Oxytocin
Outcome
Not applicableOxytocin binding sites in dorsal horn
Study
ratn: not reported in source
spinal cord sections (autoradiography)
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
Oxytocin binding sites were detected on all transverse sections in the dorsal horn, where labelling was scattered over laminae I and II.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin binding sites were detected by autoradiography on films and emulsion-coated sections in the spinal cord of adult and postnatal rats from C8 to L2, using a highly selective 125I-labelled oxytocin antagonist.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0813093601
02LabNot a test of Oxytocin aloneEx vivo tissueMechanism
In rat spinal cord, oxytocin binding sites labelled the intermediolateral cell column, the central grey (lamina X) and the nucleus intercalatus.
In plain wordsIn lab tests on rat spinal cord, oxytocin binding sites were found in the areas that control automatic body functions.
Peptide
Oxytocin
Outcome
Not applicableOxytocin binding sites in autonomic areas
Study
ratn: not reported in source
spinal cord sections (autoradiography)
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
The autonomic areas, i.e. the intermediolateral cell column, the central grey (lamina X) and the nucleus intercalatus were labelled.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin binding sites were detected by autoradiography on films and emulsion-coated sections in the spinal cord of adult and postnatal rats from C8 to L2, using a highly selective 125I-labelled oxytocin antagonist.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0813093602
03LabNot a test of Oxytocin aloneEx vivo tissueMechanism
In rat spinal cord, binding in the intermediolateral cell column was most frequent on sections from T9 to T11 in adult rats and T7 to T8 in postnatal rats.
In plain wordsIn lab tests on rat spinal cord, binding sat at different spinal levels in adult and young rats.
Peptide
Oxytocin
Outcome
Not applicableSegmental distribution of binding in intermediolateral cell column
Study
ratn: not reported in source
spinal cord sections (autoradiography)
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
Binding in the intermediolateral cell column was most frequently observed on sections from T9 to T11 in adult and T7 to T8 in postnatal rats.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin binding sites were detected by autoradiography on films and emulsion-coated sections in the spinal cord of adult and postnatal rats from C8 to L2, using a highly selective 125I-labelled oxytocin antagonist.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0813093603
04LabNot a test of Oxytocin aloneEx vivo tissueMechanism
In rat spinal cord, oxytocin binding sites were highly concentrated on cell bodies of putative sympathetic preganglionic neurons, but not all of these cells were labelled.
In plain wordsIn lab tests on rat spinal cord, oxytocin binding sites were dense on nerve cell bodies of the sympathetic system.
Peptide
Oxytocin
Outcome
Not applicableBinding on putative sympathetic preganglionic neurons
Study
ratn: not reported in source
spinal cord sections (autoradiography)
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
In this location, oxytocin binding sites were highly concentrated on cell bodies of putative sympathetic preganglionic neurons; however, not all of these cells were labelled.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin binding sites were detected by autoradiography on films and emulsion-coated sections in the spinal cord of adult and postnatal rats from C8 to L2, using a highly selective 125I-labelled oxytocin antagonist.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0813093604
05LabNot a test of Oxytocin aloneEx vivo tissueMechanism
In rat spinal cord, diffuse labelling of oxytocin binding sites occurred on the dorsal part of the central grey, mainly between T8 and L2.
In plain wordsIn lab tests on rat spinal cord, oxytocin binding sites were spread thinly in the central grey area.
Peptide
Oxytocin
Outcome
Not applicableDiffuse binding in dorsal central grey
Study
ratn: not reported in source
spinal cord sections (autoradiography)
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
Diffuse labelling occurred on the dorsal part of the central grey, mainly between T8 and L2.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin binding sites were detected by autoradiography on films and emulsion-coated sections in the spinal cord of adult and postnatal rats from C8 to L2, using a highly selective 125I-labelled oxytocin antagonist.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0813093605
06LabNot a test of Oxytocin aloneEx vivo tissueMechanism
In rat spinal cord, isolated labelled cells of the nucleus intercalatus were scattered between the central canal and the intermediolateral cell column.
In plain wordsIn lab tests on rat spinal cord, a few cells of the nucleus intercalatus carried oxytocin binding sites.
Peptide
Oxytocin
Outcome
Not applicableBinding on nucleus intercalatus cells
Study
ratn: not reported in source
spinal cord sections (autoradiography)
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
Isolated labelled cells belonging to the nucleus intercalatus were scattered between the central canal and the intermediolateral cell column.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin binding sites were detected by autoradiography on films and emulsion-coated sections in the spinal cord of adult and postnatal rats from C8 to L2, using a highly selective 125I-labelled oxytocin antagonist.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0813093606
07LabNot a test of Oxytocin aloneEx vivo tissueMechanism
In rat spinal cord, oxytocin binding sites were found on some motoneurons of the lateral group of T12-T13, but only in postnatal rats.
In plain wordsIn lab tests on rat spinal cord, oxytocin binding sites were found on some motor nerve cells, only in young rats.
Peptide
Oxytocin
Outcome
Not applicableBinding on motoneurons of lateral group T12-T13
Study
ratn: not reported in source
spinal cord sections (autoradiography)
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
In addition, oxytocin binding sites were found on some motoneurons of the lateral group of T12-T13, but only in postnatal rats.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin binding sites were detected by autoradiography on films and emulsion-coated sections in the spinal cord of adult and postnatal rats from C8 to L2, using a highly selective 125I-labelled oxytocin antagonist.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0813093607

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 20:03 UTC
Study results updated
Version 1
9 Oct 2026, 02:51 UTC
First added · source update from Europe PMC

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