Skip to content

Study · Measured the body's own peptide · 1993

3 results

Comparison of immunohistochemical localization of [Met5] enkephalin-Arg6-Gly7-Leu8, vasoactive intestinal polypeptide and tyrosine hydroxylase in the major pelvic ganglion of the rat.

Karhula T, Soinila S, Häppäolä O

Neuroscience1 May 1993Cited by 3 (Europe PMC)

PMID8100047 (opens in a new tab)DOI10.1016/0306-4522(93)90397-x (opens in a new tab)PepBankPUB-08100047
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    The rat major pelvic ganglion contained neurons that were immunoreactive for vasoactive intestinal polypeptide, separate from neurons immunoreactive for tyrosine hydroxylase.

    In plain wordsIn rats, some nerve cells in a pelvic nerve cluster contain the body's own VIP, separate from cells that contain tyrosine hydroxylase.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP immunoreactive neurons in the major pelvic ganglion
    Study

    ratn: not reported in source

    rat major pelvic ganglion
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    The major pelvic ganglion contained neurons immunoreactive either for tyrosine hydroxylase or vasoactive intestinal polypeptide.
    1 context sentence
    Summary · context
    Immunohistochemical double staining and elution-restaining techniques were used to investigate the distribution of [Met5]enkephalin-Arg6-Gly7-Leu8 in correlation with tyrosine hydroxylase and vasoactive intestinal polypeptide.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the rat major pelvic ganglion, most [Met5]enkephalin-Arg6-Gly7-Leu8-immunoreactive principal cells had no VIP immunoreactivity, but a few contained both.

    In plain wordsIn rats, most enkephalin-containing nerve cells in a pelvic nerve cluster lacked the body's own VIP, but a few had both.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableCo-localization of VIP with [Met5]enkephalin-Arg6-Gly7-Leu8
    Study

    ratn: not reported in source

    rat major pelvic ganglion
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    The majority of [Met5]enkephalin-Arg6-Gly7-Leu8-immunoreactive principal cells were non-immunoreactive for vasoactive intestinal polypeptide, but a few of them also contained vasoactive intestinal polypeptide.
    1 context sentence
    Summary · context
    Immunohistochemical double staining and elution-restaining techniques were used to investigate the distribution of [Met5]enkephalin-Arg6-Gly7-Leu8 in correlation with tyrosine hydroxylase and vasoactive intestinal polypeptide.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the rat major pelvic ganglion, [Met5]enkephalin-Arg6-Gly7-Leu8-immunoreactive pericellular fibre plexuses surrounded VIP-immunoreactive principal neurons.

    In plain wordsIn rats, enkephalin-containing nerve fibres wrapped around nerve cells that contain the body's own VIP.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableEnkephalin-peptide fibre plexuses around VIP-immunoreactive neurons
    Study

    ratn: not reported in source

    rat major pelvic ganglion
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    [Met5]Enkephalin-Arg6-Gly7-Leu8-immunoreactive pericellular fiber plexuses were found around tyrosine hydroxylase- and vasoactive intestinal polypeptide-immunoreactive principal neurons
    1 context sentence
    Summary · context
    Immunohistochemical double staining and elution-restaining techniques were used to investigate the distribution of [Met5]enkephalin-Arg6-Gly7-Leu8 in correlation with tyrosine hydroxylase and vasoactive intestinal polypeptide.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.