Skip to content

Study · Animal study (in vivo) · rabbit · 1993

4 results

Effect of dermorphin on behavior and hippocampal electrical activity in rabbits.

Fontani G, Vergnani L, Salvadori S, Voglino N, Aloisi AM, Portaluppi F, degli Uberti EC

Life sciences1 Jan 1993Cited by 6 (Europe PMC)

PMID8093805 (opens in a new tab)DOI10.1016/0024-3205(93)90224-q (opens in a new tab)PepBankPUB-08093805
Publisher pagePubMedAsk about this study
Jump to 4 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In male rabbits, dermorphin strongly increased quiet immobility compared with control periods.

    In plain wordsIn rabbits, dermorphin increased quiet immobility compared with control periods.

    Peptide
    Dermorphin
    Outcome
    IncreaseQuiet immobility
    Study

    rabbitn: not reported in source

    Male rabbits
    Comparator
    Control periods
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    0.4 mg/kg · intravenousAs given in this study (rabbit).

    Source sentences

    Summary
    Behavior showed a strong increase in quiet immobility and a concomitant reduction in voluntary activities as compared to control periods.
    1 context sentence
    Summary · context
    Dermorphin, a naturally occurring heptapeptide that selectively binds to mu-opioid receptors, was injected intravenously 0.4 mg/kg in male rabbits.
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In male rabbits, dermorphin reduced voluntary activities compared with control periods.

    In plain wordsIn rabbits, dermorphin reduced voluntary activities compared with control periods.

    Peptide
    Dermorphin
    Outcome
    DecreaseVoluntary activities
    Study

    rabbitn: not reported in source

    Male rabbits
    Comparator
    Control periods
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    0.4 mg/kg · intravenousAs given in this study (rabbit).

    Source sentences

    Summary
    Behavior showed a strong increase in quiet immobility and a concomitant reduction in voluntary activities as compared to control periods.
    1 context sentence
    Summary · context
    Dermorphin, a naturally occurring heptapeptide that selectively binds to mu-opioid receptors, was injected intravenously 0.4 mg/kg in male rabbits.
  3. 03AnimalAnimal study (in vivo)Activity measurement

    In male rabbits, dermorphin did not affect the hippocampal electrical activity pattern compared with control periods.

    In plain wordsIn rabbits, dermorphin did not affect the hippocampal electrical activity pattern compared with control periods.

    Peptide
    Dermorphin
    Outcome
    No significant changeHippocampal electrical activity pattern
    Study

    rabbitn: not reported in source

    Male rabbits
    Comparator
    Control periods
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    0.4 mg/kg · intravenousAs given in this study (rabbit).

    Source sentences

    Summary
    Treatment did not affect either the pattern or the frequency of hippocampal electrical activity.
    1 context sentence
    Summary · context
    Dermorphin, a naturally occurring heptapeptide that selectively binds to mu-opioid receptors, was injected intravenously 0.4 mg/kg in male rabbits.
  4. 04AnimalAnimal study (in vivo)Activity measurement

    In male rabbits, dermorphin did not affect hippocampal electrical activity frequency compared with control periods.

    In plain wordsIn rabbits, dermorphin did not affect hippocampal electrical activity frequency compared with control periods.

    Peptide
    Dermorphin
    Outcome
    No significant changeHippocampal electrical activity frequency
    Study

    rabbitn: not reported in source

    Male rabbits
    Comparator
    Control periods
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    0.4 mg/kg · intravenousAs given in this study (rabbit).

    Source sentences

    Summary
    Treatment did not affect either the pattern or the frequency of hippocampal electrical activity.
    1 context sentence
    Summary · context
    Dermorphin, a naturally occurring heptapeptide that selectively binds to mu-opioid receptors, was injected intravenously 0.4 mg/kg in male rabbits.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.