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Study · Ex vivo tissue · helix lucorum · 1994

5 results

[The effect of the delta sleep peptide and serotonin on the neurons of the snail].

Karpenko LD, Aroian EV, Mendzheritskiĭ AM, Filin NN

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova1 Mar 1994

PMID8023575 (opens in a new tab)PepBankPUB-08023575

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In identified snail neurons, DSIP inhibited spontaneously active neurons.

    In plain wordsIn snail nerve cells in the lab, DSIP reduced the activity of cells that fire on their own.

    Outcome
    DecreaseFiring of spontaneously active neurons
    Study

    Helix lucorumn: not reported in source

    semi-intact preparation with identified neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    DSIP inhibited spontaneously active neurons
    1 context sentence
    Summary · context
    The experiments were performed on semi-intact preparations from Helix lucorum L.
  2. 02LabEx vivo tissueActivity measurement

    In identified snail neurons, DSIP reduced the responses of silent cells to depolarizing currents.

    In plain wordsIn snail nerve cells in the lab, DSIP weakened how silent cells answered electrical stimulation.

    Outcome
    DecreaseResponse of silent cells to depolarizing currents
    Study

    Helix lucorumn: not reported in source

    semi-intact preparation with identified neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    reduced responses of silent cells to depolarizing currents and tactile stimuli.
    1 context sentence
    Summary · context
    The experiments were performed on semi-intact preparations from Helix lucorum L.
  3. 03LabEx vivo tissueActivity measurement

    In identified snail neurons, DSIP reduced the responses of silent cells to tactile stimuli.

    In plain wordsIn snail nerve cells in the lab, DSIP weakened how silent cells answered touch stimuli.

    Outcome
    DecreaseResponse of silent cells to tactile stimuli
    Study

    Helix lucorumn: not reported in source

    semi-intact preparation with identified neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    reduced responses of silent cells to depolarizing currents and tactile stimuli.
    1 context sentence
    Summary · context
    The experiments were performed on semi-intact preparations from Helix lucorum L.
  4. 04LabEx vivo tissueActivity measurement

    In identified snail neurons, the DSIP effects were dose-dependent.

    In plain wordsIn snail nerve cells in the lab, the effects of DSIP depended on the dose.

    Outcome
    Not applicableDose dependence of DSIP effects on neurons
    Study

    Helix lucorumn: not reported in source

    semi-intact preparation with identified neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    DSIP effects were dose-dependent.
    1 context sentence
    Summary · context
    The experiments were performed on semi-intact preparations from Helix lucorum L.
  5. 05LabEx vivo tissueActivity measurement

    In identified snail neurons, DSIP and serotonin had mutually opposite effects.

    In plain wordsIn snail nerve cells in the lab, DSIP and serotonin had opposite effects.

    Outcome
    Not applicableDSIP versus serotonin effect on neurons
    Study

    Helix lucorumn: not reported in source

    semi-intact preparation with identified neurons
    Comparator
    Serotonin (5-HT)
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    5-HT excited neurons in question. DSIP and 5-HT had the mutually opposite effects on the identified neurons.
    1 context sentence
    Summary · context
    The experiments were performed on semi-intact preparations from Helix lucorum L.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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