In ovariectomised ewes given an oxytocin challenge on day 10 of a simulated cycle, the mean PGFM response was not changed by the oestradiol concentration given.
In plain wordsIn ewes, the amount of oestradiol given did not change the prostaglandin metabolite response to an oxytocin dose on day 10.
- Peptide
- Oxytocin
- Outcome
- No significant changePGFM response to oxytocin challenge on day 10
- Study
sheepn: not reported in source
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
Source sentences
On day 10 only one ewe in each group exhibited a PGFM response to oxytocin, and the mean response was unaffected by the concentration of oestradiol administered.
2 context sentences(design, population, supporting numbers)
Ewes were then treated for up to 12 days with progesterone (24 mg day-1 maximum) with or without oestradiol (both hormones administered in 1 ml of corn oil i.m. at 8 h intervals) in a pattern known to simulate natural plasma profiles of the oestrous cycle.
Subgroups of four ewes from each treatment group were given 1 microgram of oxytocin (i.v.) on day 10, 11 or 12 of the simulated cycle, and endometrial oxytocin receptor concentrations were determined in samples collected within 3 h of oxytocin administration.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.