In frog glomeruli, oxytocin ranked above arginine vasopressin and DDAVP, and below arginine vasotocin and several antagonists, in recognition by vasotocin receptors.
In plain wordsIn frog kidney tissue, oxytocin was recognised by vasotocin receptors less well than vasotocin but better than vasopressin.
- Peptide
- Oxytocin
- Outcome
- Not applicableOxytocin recognition by frog glomerular vasotocin receptors
- Study
frog (Rana ridibunda)n: not reported in source
microdissected glomeruli from collagenase-treated kidneys- Outcome group
- Receptor activity and mechanism · Kidney and urinary
- Studied dose
- Dose not stated
Source sentences
Glomerular receptors exhibited the following stereospecificity for recognition of vasotocin analogues: Tyr-NH2(9)-LA-V1a > 125I-OVTA > arginine vasotocin (AVT) > or = [d(CH2)5Tyr-(Me)2]AVP > OVTA > or = [Phe2,Orn8]VT > oxytocin (OT) > or = [d(CH2)5-Sar7]AVP > desGly9[d(CH2)5Tyr(Et)2]VAVP > or = [d(C…
1 context sentence(design, population, supporting numbers)
Vasotocin receptors were investigated in glomeruli and nephron segments microdissected from collagenase-treated kidneys of Rana ridibunda, using [d(CH2)5Tyr(Me)2,Thr4,Orn8,125I-Tyr-NH2(9)]vasotocin (125I-OVTA) as a radioligand.