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Study · Measured the body's own peptide · 1994

4 results

Effects of oophorectomy and estrogen treatment on basal levels and 24-h profiles of oxytocin.

Nathorst-Böös J, Stock S, von Schoultz B

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology1 Jun 1994Cited by 2 (Europe PMC)

PMID7942080 (opens in a new tab)DOI10.3109/09513599409058034 (opens in a new tab)PepBankPUB-07942080
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialOther

    In 95 women after hysterectomy, removal of the ovaries did not reduce basal oxytocin levels in any of the investigated groups.

    In plain wordsIn 95 women after hysterectomy, removing the ovaries did not lower the body's own oxytocin levels.

    Peptide
    Oxytocin
    Outcome
    No significant changeBasal oxytocin level after oophorectomy
    Study

    n = 95

    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Removal of the ovaries did not reduce oxytocin levels in any of the investigated groups.
    1 context sentence
    Summary · context
    Basal levels of oxytocin were measured in 95 women who had undergone hysterectomy and who were divided into three groups: group A (n = 30), oophorectomized (BSO), not on HRT; group B (n = 32), BSO, receiving HRT; and group C (n = 33), ovaries preserved and not receiving HRT.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialOther

    In nine women, no specific rhythmic or pulsatile pattern of 24-h oxytocin was found before or after hysterectomy, with or without oophorectomy.

    In plain wordsIn nine women, the body's own oxytocin showed no clear daily rhythm or pulse pattern before or after surgery.

    Peptide
    Oxytocin
    Outcome
    No significant change24-h oxytocin profile pattern
    Study

    n = 9

    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    When 24-h values were analyzed, no specific rhythmic or pulsatile pattern before or after hysterectomy, with or without simultaneous oophorectomy, was found.
    1 context sentence
    Summary · context
    The 24-h profiles of oxytocin were measured in nine women before and after hysterectomy.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelNon-randomized trialOther

    In women after hysterectomy, exogenous estrogen administration was associated with increased oxytocin levels.

    In plain wordsIn women after hysterectomy, estrogen treatment was linked to higher levels of the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin level with exogenous estrogen
    Study

    n: not reported in source

    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Exogenous estrogen administration was associated with increased oxytocin levels and negative correlation between oxytocin and follicle stimulating hormone/luteinizing hormone levels was found.
    1 context sentence
    Summary · context
    Thereafter, three of the four oophorectomized women started replacement therapy with transdermal estradiol 50 micrograms/day.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelNon-randomized trialOther

    In women after hysterectomy, oxytocin levels correlated negatively with follicle stimulating hormone and luteinizing hormone levels.

    In plain wordsIn women after hysterectomy, the body's own oxytocin levels were linked to lower levels of two pituitary hormones, FSH and LH.

    Peptide
    Oxytocin
    Outcome
    DecreaseCorrelation of oxytocin with FSH and LH
    Study

    n: not reported in source

    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    negative correlation between oxytocin and follicle stimulating hormone/luteinizing hormone levels was found.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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