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Study · Measured the body's own peptide · 1994

1 result

Straight leg raising test and lumbar cerebrospinal fluid levels of vasoactive intestinal polypeptide and somatostatin in patients with low back pain.

Grönblad M, Lukinmaa A, Jolkkonen J, Schugk P, Seitsalo S, Korkala O, Ervasti H

Spine1 Jul 1994Cited by 6 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In 77 patients with low back pain and leg pain, cerebrospinal fluid levels of the body's own VIP were altered in patients with a positive straight leg raising test.

    In plain wordsIn people with back and leg pain, the body's own VIP levels in spinal fluid were linked to a positive leg-raising test.

    Outcome
    Direction not reportedCSF VIP levels by straight leg raising test
    Study

    n = 77

    Comparator
    Negative straight leg raising test
    Outcome group
    Pain · Nervous system and cognition

    Source sentences

    Summary
    In the present mixed back pain patient population, which included radicular pain symptoms due to disc herniation and lumbar stenosis, alterations in vasoactive intestinal peptide levels in particular were observed with a positive straight leg raising test.
    2 context sentences
    Summary · context
    Straight leg raising was recorded before myelography in 77 patients.
    Summary · context
    At myelography, samples of cerebrospinal fluid were drawn and later analyzed for neuropeptides vasoactive intestinal polypeptide and somatostatin.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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