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Study · Animal study (in vivo) · souslik · 1993

4 results

The role of dermorphin in the regulation of the processes of hibernation in mammals.

Sollertinskaya TN, Nuritdinov EN, Obukhova MF

Neuroscience and behavioral physiology1 Sept 1993

PMID7901800 (opens in a new tab)DOI10.1007/bf01183008 (opens in a new tab)PepBankPUB-07901800
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In sousliks, dermorphin administration accompanied a fall in body temperature.

    In plain wordsIn sousliks, body temperature fell after dermorphin administration.

    Peptide
    Dermorphin
    Outcome
    DecreaseBody temperature
    Study

    souslikn: not reported in source

    Sousliks
    Outcome group
    Body temperature · Whole body
    Studied dose
    0.1 mu/g · subcutaneousAs given in this study (souslik).

    Source sentences

    Summary
    The administration of dermorphin (0.1 mu/g, subcutaneously) is accompanied by a fall in body temperature, slowing of the baseline vegetative indices, and the sinking of the animal into a sleep-like state.
    1 context sentence
    Summary · context
    Data are presented in this paper regarding the influence of the opioid peptide, dermorphin, and its conjugate on the conditioned reflex activity of sousliks.
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In sousliks, dermorphin administration accompanied slowing of baseline vegetative indices.

    In plain wordsIn sousliks, baseline autonomic measures slowed after dermorphin administration.

    Peptide
    Dermorphin
    Outcome
    DecreaseBaseline vegetative indices
    Study

    souslikn: not reported in source

    Sousliks
    Outcome group
    Autonomic function · Whole body
    Studied dose
    0.1 mu/g · subcutaneousAs given in this study (souslik).

    Source sentences

    Summary
    The administration of dermorphin (0.1 mu/g, subcutaneously) is accompanied by a fall in body temperature, slowing of the baseline vegetative indices, and the sinking of the animal into a sleep-like state.
    1 context sentence
    Summary · context
    Data are presented in this paper regarding the influence of the opioid peptide, dermorphin, and its conjugate on the conditioned reflex activity of sousliks.
  3. 03AnimalAnimal study (in vivo)Activity measurement

    In sousliks, dermorphin administration accompanied entry into a sleep-like state.

    In plain wordsIn sousliks, dermorphin administration accompanied a sleep-like state.

    Peptide
    Dermorphin
    Outcome
    IncreaseSleep-like state
    Study

    souslikn: not reported in source

    Sousliks
    Outcome group
    Sleep · Sleep
    Studied dose
    0.1 mu/g · subcutaneousAs given in this study (souslik).

    Source sentences

    Summary
    The administration of dermorphin (0.1 mu/g, subcutaneously) is accompanied by a fall in body temperature, slowing of the baseline vegetative indices, and the sinking of the animal into a sleep-like state.
    1 context sentence
    Summary · context
    Data are presented in this paper regarding the influence of the opioid peptide, dermorphin, and its conjugate on the conditioned reflex activity of sousliks.
  4. 04AnimalAnimal study (in vivo)Safety outcome

    In sousliks, a substantial disturbance of conditioned reflex activity appeared in the delayed period after dermorphin.

    In plain wordsIn sousliks, conditioned reflex activity showed a substantial delayed disturbance after dermorphin.

    Peptide
    Dermorphin
    Outcome
    Direction not reportedDelayed conditioned reflex disturbance
    Study

    souslikn: not reported in source

    Sousliks
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.1 mu/g · subcutaneousAs given in this study (souslik).

    Source sentences

    Summary
    A substantial disturbance of conditioned reflex activity was identified in the late period (delayed effects).
    1 context sentence
    Summary · context
    Data are presented in this paper regarding the influence of the opioid peptide, dermorphin, and its conjugate on the conditioned reflex activity of sousliks.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

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