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Study · Animal study (in vivo) · dog · 1994

2 results

Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles.

Jacks T, Hickey G, Judith F, Taylor J, Chen H, Krupa D, Feeney W, Schoen W, Ok D, Fisher M

The Journal of endocrinology1 Nov 1994Cited by 48 (Europe PMC)

PMID7830002 (opens in a new tab)DOI10.1677/joe.0.1430399 (opens in a new tab)PepBankPUB-07830002
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In beagles, GHRP‑6 was less potent than L-692,585 for peak GH responses.

    In plain wordsIn dogs, GHRP‑6 was less potent than L-692,585 for peak growth hormone responses.

    Peptide
    GHRP-6
    Outcome
    DecreasePeak GH potency
    Study

    dogn: not reported in source

    beagles
    Comparator
    L-692,585
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Based on peak responses and total GH release, L-692,585 was 10- to 20-fold and 2- to 2.5-fold more potent than L-692,429 and the growth hormone releasing peptide, GHRP-6, respectively.
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In beagles, GHRP‑6 was less potent than L-692,585 for total GH release.

    In plain wordsIn dogs, GHRP‑6 was less potent than L-692,585 for total growth hormone release.

    Peptide
    GHRP-6
    Outcome
    DecreaseTotal GH release potency
    Study

    dogn: not reported in source

    beagles
    Comparator
    L-692,585
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Based on peak responses and total GH release, L-692,585 was 10- to 20-fold and 2- to 2.5-fold more potent than L-692,429 and the growth hormone releasing peptide, GHRP-6, respectively.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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