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Study · Not a test of the peptide alone · 1995

2 results

Sex differences in and effects of estrogen on oxytocin receptor messenger ribonucleic acid expression in the ventromedial hypothalamus.

Bale TL, Dorsa DM

Endocrinology1 Jan 1995Cited by 74 (Europe PMC)

PMID7828541 (opens in a new tab)DOI10.1210/endo.136.1.7828541 (opens in a new tab)PepBankPUB-07828541
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In rats, males expressed higher levels of oxytocin receptor mRNA in the ventromedial hypothalamus than females.

    In plain wordsIn rats, males had more oxytocin receptor messenger RNA in a brain area than females.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin receptor mRNA in the VMH, male versus female rats
    Study

    ratn: not reported in source

    ventromedial hypothalamus in situ hybridization
    Comparator
    Female rats
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    The results of these studies showed that male rats expressed higher levels of OR mRNA in the VMH than females.
    1 context sentence
    Summary · context
    This study was designed to compare levels of OR messenger RNA (mRNA) in the VMH of male and female rats and to study the effects of estrogen treatment on mRNA levels in the VMH of female rats.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In ovariectomized female rats, estrogen treatment increased oxytocin receptor mRNA in the ventromedial hypothalamus compared with oil-treated or intact females.

    In plain wordsIn female rats, estrogen raised oxytocin receptor messenger RNA in a brain area compared with oil treatment or no treatment.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin receptor mRNA in the VMH after estrogen in ovariectomized females
    Study

    ratn: not reported in source

    ventromedial hypothalamus in situ hybridization
    Comparator
    Oil-treated ovariectomized or intact females
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Estrogen-treated ovariectomized females exhibited significantly greater expression in the VMH than either oil-treated or intact females.
    1 context sentence
    Summary · context
    This study was designed to compare levels of OR messenger RNA (mRNA) in the VMH of male and female rats and to study the effects of estrogen treatment on mRNA levels in the VMH of female rats.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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