In thalassaemia major, pooled continuous hormone replacement including male hCG increased BMD more than on/off courses.
In plain wordsIn thalassaemia major, pooled continuous hormone replacement including male hCG increased bone density more than on/off courses.
- Outcome
- IncreaseBone mineral density increase
- Study
n: not reported in source
- Comparator
- On/off treatment courses
- Outcome group
- Bone and joint · Musculoskeletal
Measurements
- P value for BMD increase
- 0.01 p value
- continuous replacement versus on/off treatment courses
Source sentences
In the prospective study the continuous replacement group increased BMD and BMC values more than the on/off treatment courses (P = 0.01).
2 context sentences(design, population, supporting numbers)
The continuous schemes comprised either transdermal oestradiol (100 micrograms) plus medroxyprogesterone for females or hCG to produce serum testosterone concentrations within normal range, for males.
Bone mineral density (BMD) and bone mineral content (BMC) of lumbar spine and distal end of radius were measured by dual-energy X-ray absorptiometry.
In this study, hCG (human chorionic gonadotropin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking hCG (human chorionic gonadotropin).