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Study · Measured the body's own peptide · 1994

3 results

Colocalization of tyrosine hydroxylase with oxytocin or vasopressin in neurons of the human paraventricular and supraoptic nucleus.

Panayotacopoulou MT, Raadsheer FC, Swaab DF

Brain research. Developmental brain research1 Nov 1994Cited by 30 (Europe PMC)

PMID7697871 (opens in a new tab)DOI10.1016/0165-3806(94)90179-1 (opens in a new tab)PepBankPUB-07697871
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyMechanism

    In the adult and neonatal human PVN and SON, TH-immunoreactive perikarya were also positive for OXT or VP.

    In plain wordsIn human brain tissue, cells making the enzyme tyrosine hydroxylase also contained the body's own oxytocin or vasopressin.

    Peptide
    Oxytocin
    Outcome
    Not applicableColocalization of tyrosine hydroxylase with OXT or VP
    Study

    n: not reported in source

    Human PVN and SON tissue sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    We observed that TH-immunoreactive(IR) perikarya in the human PVN and SON were also positive for OXT or VP.
    1 context sentence
    Summary · context
    Adjacent paraffin sections were incubated simultaneously with two antibodies: a polyclonal against TH and a monoclonal against OXT or VP and stained with a double peroxidase-antiperoxidase/alkaline phosphatase method.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyMechanism

    In neonatal human PVN and SON, only few TH-immunoreactive neurons were also positive for OXT.

    In plain wordsIn newborn human brain tissue, few enzyme-containing cells also held the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    Not applicableOXT colocalization with TH in neonates
    Study

    n: not reported in source

    Human PVN and SON tissue sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    In the neonates the majority of the TH-IR perikarya was also stained for VP, while only few TH-IR neurons were also positive for OXT.
    1 context sentence
    Summary · context
    Adjacent paraffin sections were incubated simultaneously with two antibodies: a polyclonal against TH and a monoclonal against OXT or VP and stained with a double peroxidase-antiperoxidase/alkaline phosphatase method.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyMechanism

    In adult human PVN and SON, the majority of double-stained TH-immunoreactive neurons colocalized OXT.

    In plain wordsIn adult human brain tissue, most enzyme-containing cells that were double-stained also held the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    Not applicableOXT colocalization with TH in adults
    Study

    n: not reported in source

    Human PVN and SON tissue sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The opposite was observed in the adults, where the majority of the double-stained TH-IR neurons colocalizes OXT while only few TH-IR perikarya appear to contain VP.
    1 context sentence
    Summary · context
    Adjacent paraffin sections were incubated simultaneously with two antibodies: a polyclonal against TH and a monoclonal against OXT or VP and stained with a double peroxidase-antiperoxidase/alkaline phosphatase method.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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